Organic Chemistry DT Chemistry Spellchecker Organic Chemistry Editorial Board Information For Editorial Board Members Order Information Index of Authors   Now Available! ChemTracts Online

Chemtracts Authors Below is an index of authors who have written for Chemtracts. Click a letter to jump to an author's last name. Click the title of an article to jump to the abstract. To see the full-text, either login, subscribe or use the pay-per-view option. A ~ B ~ C ~ D ~ E ~ F ~ G ~ H ~ I ~ J ~ K ~ L ~ M ~ N ~ O ~ P ~ Q ~ R ~ S ~ T ~ U ~ V ~ W ~ X ~ Y ~ Z Touraj Abdollahi -- Thomas Jefferson Medical College, Thomas Jefferson University Smac, a Mitochondrial Protein that Promotes Cytochrome c-Dependent Caspase Activation by Eliminating IAP Inhibition Mirit I. Aladjem -- National Cancer Institute Drosophila ORC Specifically Binds to ACE3, an Origin of DNA Replication Control Element Functionally Distinct, Sequence-Specific Replicator and Origin Elements Are Required for Drosophila Chorion Gene Amplification Mark Allen -- Montana State University Phage Display Libraries: A Technique for Peptide-Mineral Discovery Amy L. Altman -- Vanderbilt University Identification of a Binding Region for Human Origin Recognition Complex Proteins 1 and 2 that Coincides with an Origin of DNA Replication Maria Alvim-Gaston -- University of Mississippi New Type of Febrifugine Analogues, Bearing a Quinolizidine Moiety, Show Potent Antimalarial Activity Against Plasmodium Malaria Parasite A Light-Inactivated Antibiotic Robert J. Angelici -- Iowa State University, Ames Laboratory, U.S. Department of Energy Novel Chiral Functionalized N-Heterocyclic Carbenes and Their Rhodium(I) Complexes: Applications in Asymmetric Catalysis Sayura Aoyagi -- University of Rochester Medical Center Accessibility of Nucleosomal DNA to V(D)J Cleavage Is Modulated by RSS Positioning and HMG 1 Accessibility of Nucleosomal DNA to V(D)J Cleavage Is Modulated by RSS Positioning and HMG 1 Giovanni Appendino -- Universita del Piemonte Orientale, Novara and Universit a di Parma The Synthesis of the Thapsigargins The Synthesis of the Anti-Malarial Natural Product Polysphorin and Analogues Using Polymer-Supported Reagents and Scavengers Resurrecting the Cornforth Model for Carbonyl Addition: Studies on the Origin of the 1,2-Asymmetric Induction in Enolate Addition to Heteroatom-Substituted Aldehydes Isopavines as a New Class of Morphinomimetics The First Stereoselective Total Synthesis of Quinine The Vinylogous Intramolecular Morita-Baylis-Hillman Reaction Molecular Recognition of Carbonyl Compounds Using Aluminum Tris(2,6-diphenylphenoxide) (ATPH): New Regio- and Stereoselective Alkylation of a,b-Unsaturated Carbonyl Compounds A New Method for the One-Step Synthesis of a,a-Unsaturated Carbonyl Systems from Saturated Alcohols and Carbonyl Compounds The Synthesis of Bisorbicillinoids. An Amazing Self-Assembly of Simple Compounds into Highly Complex Natural Products The Total Synthesis of Frondosin B V.S. Ananthanarayanan -- McMaster University, Hamilton, Ontario Polar Residues Drive the Association of Polyleucine Transmembrane Helices Highly Purified Scavenger Receptor Class B, Type I Reconstituted into Phosphatidylcholine/Cholesterol Liposomes Mediates High-Affinity Binding and Selective Lipid Uptake Rational Discovery of Novel Antagonists of Retinoic Acid Receptor Anthony T. Annunziato -- Boston College The N-Terminal Domains of Histones H3 and H4 Are Not Necessary for Chromatin Assembly Factor-1-Mediated Nucleosome Assembly onto Replicated DNA in Vitro Histone Octamer Tsransfer by a Chromatin Remodeling Complex The RCAF Complex Mediates Chromatin Assembly During DNA Replication and Repair Eric A. Archer -- University of Texas at Austin Second Generation Light-Driven Molecular Motors: Unidirectional Rotation Controlled by a Single Stereogenic Center with Near-Perfect Photoequilibria and Acceleration of the Speed of Rotation by Structural Modification Trevor K. Archer -- National Institute of Environmental Health Sciences, National Institutes of Health Transcriptional Specificity of Human SWI/SNF BRG1 and BRM Chromatin Remodeling Complexes Fabio Arnesano -- Magnetic Resonance Center CERM and Department of Chemistry, University of Florence Molecular Basis of Metal-Ion Selectivity and Ultrasensitivity of Metalloregulatory Proteins Jeffrey Aube -- University of Kansas Total Syntheses of Martinella Alkaloids Oxaziridines as N- and O-Functionalization Reagents Juan Ausio -- University of Victoria Chromodomains Are Protein-RNA Interaction Modules Global Histone Acetylation and Deacetylation in Yeast Virus Infection Leads to Localized Hyperacetylation of Histones H3 and H4 at the IFN- Promoter Regions of Variant Histone His2AvD Required for Drosophila Development Terry T.-L. Au-Yeung -- The Hong Kong Polytechnic University Towards Highly Air-Stable Phosphorus Ligand and Metal-Catalyst Precursors for Cross-Coupling Reactions with Unactivated Aryl Chlorides Luciana Auzzas -- Universita di Parma, ICB-CNR, Sassari and Universita del Piemonte Orientale, Novara Isopavines as a New Class of Morphinomimetics Mitchell A. Avery -- University of Mississippi Novel Tricyclic a-Alkoxyphenyl Propanoic Acid Derivatives: Dual PPARa/g Agonists with Hypolipidemic and Antidiabetic Activity Drug Delivery Systems Based on Trimethyl Lock Lactonization: Poly(ethyleneglycol) Prodrugs of Amino-Containing Compounds Potent, Low-Molecular-Weight Non Peptide Inhibitors of Matarial Aspartyl Protease Plasmepsin ll New Type of Febrifugine Analogues, Bearing a Quinolizidine Moiety, Show Potent Antimalarial Activity Against Plasmodium Malaria Parasite Pursuing a Progesterone Receptor Pharmacophore: Development of Nonsteroidal Ligands for the Progesterone Receptor A Light-Inactivated Antibiotic Structural Specificity of Chloroquine-Hematin Binding Related to Inhibition of Hematin Polymerization and Parasite Growth S. Bahmanyar -- University of California, Los Angeles Proline-Catalyzed Direct Asymmetric Aldol Reactions Catalytic Asymmetric Synthesis of anti-1,2-Diols Michael J. Baldwin -- University of Cincinnati Oxygen Activation by Nickel Complexes: Development of Oxygen-Active Ni(II)-Oximate Complexes Emily P. Balskus -- University of Cambridge Rhodium-Catalyzed Coupling of Heterocycles and Alkenes: A Novel Mechanism of C-H Activation Robert A. Bambara -- University of Rochester School of Medicine and Dentistry RPA Governs Endonuclease Switching During Processing of Okazaki Fragments in Eukaryotes E.T.W. Bampton -- University of Cambridge, Cambridge, UK A Novel Protein Complex Linking the d2 Glutamate Receptor and Autophagy: Implications for Neurodegeneration in Lurcher Mice N.A.G. Bandeira -- University of Lisbon On the Noble Gas-Induced Intersystem Crossing for the CUO Molecule: Experimental and Theoretical Investigations of CUO(Ng)n(Ng = Ar, Kr, Xe; n = 1,2,3,4) Rakeshwar Bandichhor -- University of Regensburg Cyclopropanation with Fischer Acyloxycarbene Complexes: Preparation of Cyclopropane and Cycloheptane-Fused g-Lactones The Photochemistry of 2-(1-Naphthyl)ethyl Benzoates: Cycloaddition and Intramolecular Exciplex Formation Pierluigi Barbaro -- ISSECC-CNR, Florence, Italy Highly Enantioselective Epoxidtion of cis-Olenfins by Chiral Dioxirane Highly Effective Chiral Dipyridylphosphine Ligands: Synthesis, Structural Determination, and Applications in the Ru-Catalyzed Asymmetric Hydrogenation Reactions Highly Enantioselective Rhodium-Catalyzed Hydrogenation with Monodentate ligands Mirela M. Barsan -- McGill University High-Pressure Study of Ru3(CO)12 by X-ray Diffraction, Raman, and Infrared Spectroscopy Mark R. Barvian -- Pfizer Global Research and Development, Ann Arbor Laboratories N,N-Diethanolaminomethyl Polystyrene: An Efficient Solid Support to Immobilize Boronic Acids Partha Basu -- Duquesne University Geometric Perturbation of Electronic Structure of Discrete Molybdenum(V) Cores and the Reduction Potential M.C. Bates -- McMaster University, Hamilton, Ontario Highly Purified Scavenger Receptor Class B, Type I Reconstituted into Phosphatidylcholine/Cholesterol Liposomes Mediates High-Affinity Binding and Selective Lipid Uptake Gianantonio Battistuzzi -- University of Modena and Reggio Emilia, Modena, Italy Metal-Ligand Interplay in Blue Copper Proteins Studied by 1H NMR Spectroscopy: Cu(II)-Pseudoazurin and Cu(II)-Rusticyanin A Comparison of the Inner-Sphere Reorganization Energies of Cytochromes, Iron-Sulfur Clusters and Blue Copper Proteins Robert Bau -- University of Southern California Neutron Diffraction Studies on Proteins Miguel Baya -- Laboratoire de Chimie de Coordination, Toulouse, France Precursors to Water-Soluble Dinitrogen Carriers. Synthesis of Water-Soluble Complexes of Iron(II) Containing Water-Soluble Chelating Phosphine Ligands of the Type 1,2-Bis[bis(hydroxyalkyl) phosphino]ethane Barbara Beck -- Morphochem AG, Munich, Germany New Heterocycle Synthesis by Using Bifunctional Reactants in MCR Chemistry: The Use of Arylglyoxales and Cinnamaldehyde in the Ugi-4CR and Passerini-3CR Michael J. Behe -- Lehigh University Extreme Functional Sensitivity to Conservative Amino Acid Changes on Enzyme Exteriors Tolerance of Arc Repressor to Multiple-Alanine Substitutions David E. Bergbreiter -- Texas A&M University Precipitons-Functional Protecting Groups to Facilitate Product Separation: Applications in Isoxazoline Synthesis Fabrication of Micro Reaction Cages with Tailored Properties Fourier Transform Combinatorial Chemistry Catalytic Oxidations of Alcohols Using Phenanthroline-Pd Complexes and Oxygen Robert G. Bergman -- University of California, Berkeley Encapsulation of Cationic Organometallic Guests by a Chiral Self-Assembled Supramolecular Cage: Enantioselective Binding, Dynamic Resolution, and Selective C–H Bond Activation Anna Bernardi -- University of Milano Solid-Phase Synthesis of Peptide C-Terminal Thioesters by Fmoc/t-Bu Chemistry Fmoc-Based Synthesis of Peptide-a-Thioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation Lisa M. Berreau -- Utah State University Nitrogen/Sulfur Ligands Possessing Internal Hydrogen Bond Donors: A Synthetic Strategy for Modeling Secondary Interactions at Biological Zinc Centers Craig R. Berry -- University of Minnesota-Twin Cities Syntheses and Stereoselective 1,2-Addition Reactions of Chiral Stannyl Allenamides Ivano Bertini -- Magnetic Resonance Center CERM and Department of Chemistry, University of Florence Molecular Basis of Metal-Ion Selectivity and Ultrasensitivity of Metalloregulatory Proteins Calculation of z-Coordinates and Orientational Restraints Using a Metal Binding Tag Effects of Folding on Metalloprotein Active Sites Helge Bertram -- European Molecular Biology Laboratory (EMBL), Heidelberg and University of Wurzburg, Germany A "Periodic Table" for Protein Structure Rajiv Bhalla -- University of California, Santa Cruz Calix[6]arenes and Zinc: Biomimetic Receptors for Neutral Molecules Claudio Bianchini -- ICCOM-CNR, Florence, Italy ''Oscillating'' Metallocene Catalysts: How Do They Oscillate? Continuous Flow Homogeneous Catalysis: Hydroformylation of Alkenes in Supercritical Fluid-Ionic Liquid Biphasic Mixtures Supported Ionic Liquid Catalysis-A New Concept for Homogeneous Hydroformylation Catalysis High-Activity, Single-Site Catalyst for the Alternating Copolymerization of CO2 and Propylene Oxide Fluorous Biphasic Catalysis Without Perfluorinated Solvents: Application to Pd-Mediated Suzuki and Sonogashira Couplings Enantioselective Addition of Alcohols to Ketenes Catalyzed by a Planar-Chiral Azaferrocene: Catalytic Asymmetric Synthesis of Arylpropionic Acids Enantioselective Staudinger Synthesis of b-Lactams Catalyzed by a Planar-Chiral Nucleophile The Nature of the Active Species in Bis(imino)pyridyl Cobalt Ethylene Polymerisation Catalysts Olefin Polymerization with [Bis(imino)pyridyl CoIICl2]: Generation of the Active Species Involves CoI Palladium(II) b-Agostic Alkyl Cations and Alkyl Ethylene Complexes: Investigation of Polymer Chain Isomerization Mechanisms On the Origin of Opposite Stereoselection in the Asymmetric Hydrogenation of Phenyl-and tert-Butyl-Substituted Enamides Asymmetric Hydrogenation of Enamides with Rh-BisP and Rh-MiniPHOS Catalysts: Scope, Limitations, and Mechanism Palladium-Catalyzed Arylation of Malonates and Cyanoesters Using Sterically Hindered Trialkyl-and Ferrocenyldialkylphosphine Ligands A General and Mild Copper-Catalyzed Arylation of Diethyl Malonate Asymmetric Catalysis with the Normally Unresolvable, Conformationally Dynamic 2,2¢-Bis(diphenylphosphino)-1,1¢-biphenyl (Biphep) Resolution of Pd Catalyst with tropos Biphenylphosphine (BIPHEP) Ligand by DM-DABN: Asymmetric Catalysis by an Enantiopure BIPHEP-Pd Complex Asymmetric Activation of the Pd Catalyst Bearing the tropos Biphenylphosphine (BIPHEP) Ligand with the Chiral Diaminobinaphthyl (DABN) Activator The First Example of Palladium Catalysed Non-perfectly Alternating Copolymerisation of Ethene and Carbon Monoxide Discovery of Exceptionally Efficient Catalysts for Solvent-Free Enantioselective Hetero-Diels-Alder Reaction Kinetic Studies of Migratory Insertion Reactions at the (1,3-Bis(diphenylphosphino)propane) Pd(II) Center and Their Relationship to the Alternating Copolymerization of Ethylene and Carbon Monoxide In Situ Monitoring of a Heterogeneous Palladium-Based Polyketone Catalyst Copolymers of Vinyl Epoxides with Carbon Monoxide Highly Enantioselective Epoxidtion of cis-Olenfins by Chiral Dioxirane Highly Effective Chiral Dipyridylphosphine Ligands: Synthesis, Structural Determination, and Applications in the Ru-Catalyzed Asymmetric Hydrogenation Reactions Highly Enantioselective Rhodium-Catalyzed Hydrogenation with Monodentate ligands Anja-Katrin Bielinsky -- University of Minnesota Human DNA Replication Initiation Factors, ORC and MCM, Associate with oriP of Epstein-Barr Virus Replication from oriP of Epstein-Barr Virus Requires Human ORC and Is Inhibited by Geminin? Human Origin Recognition Complex Binds to the Region of the Latent Origin of DNA Replication of Epstein-Barr Virus Burchelle Blackman -- University of Kansas Stereoselective Syntheses of Epothilones A and B via Nitrile Oxide Cycloadditions John P. Blass -- Weill Medical College of Cornell University at Burke Medical Research Institute Photoactivated g-Secretase Inhibitors Directed to the Active Site Covalently Label Presenilin 1 J. Julian Blow -- Wellcome Trust Biocentre, University of Dundee, Dundee, UK Steps Leading to the Initiation of Replication: Where We Are and Where We May Be Going Christoph H. Borchers -- University of North Carolina Introduction to Proteomics: Tools for the New Biology Christian Boulin -- European Molecular Biology Laboratory (EMBL), Heidelberg Stochastic Sensing of Organic Analytes by a Pore-Forming Protein Containing a Molecular Adapter Kara L. Bren -- University of Rochester Heme Ligation and Conformational Plasticity in the Isolated c Domain of Cytochrome cd1 Nitrite Reductase A Possible Role for the Covalent Heme-Protein Linkage in Cytochrome c Revealed via Comparison of N-Acetylmicroperoxidase-8 and a Synthetic, Monohistidine-Coordinated Heme Peptide Recent Advances in NMR Spectroscopy of Cytochromes c Heme Ligation and Conformational Plasticity in the Isolated c Domain of Cytochrome cd1 NitriteReductase Redox Thermodynamics of Low-Potential Iron-Sulfur Proteins Paul E. Brennan -- University of Cambridge, United Kingdom New Catalysts for Olefin Metathesis Catherine Brenner -- Universite de Versailles, St. Quentin, France Cytochrome c Release from Mitochondria: New Rules of the Game Ronald Breslow -- Columbia University Biomimetic Regioselective Template-Directed Functionalizations: An Update Fred Brewer -- Albert Einstein College of Medicine Cutting Edge: CD7 Delivers a Pro-Apoptotic Signal During Galectin-1-Induced T Cell Death Dominic E.A. Brittain -- University of Cambridge The First Lewis Acid-Catalyzed Allylboronate Additions to Aldehydes Annette Vitale Brown -- University of Notre Dame Lewis Acid Induced Epoxide Rearrangement for Complex Molecule Synthesis Jennifer C. Brown -- Department of Cell Biology, University of Massachusetts Medical School The Acrosome Reaction: An Example of Egg-Activated Signal Transduction in Sperm Steven D. Brown -- University of Utah Hydrodefluorination of Fluorobenzene and 1,2-Difluorobenzene under Mild Conditions over Rhodium Pyridylphosphine and Bipyridyl Complexes Tethered on a Silica-Supported Palladium Catalyst Kay M. Brummond -- University of Pittsburgh A Novel Application of a Pd(0)-Catalyzed Nucleophilic Substitution Reaction to the Regio- and Stereoselective Synthesis of Lactam Analogues of the Epothilone Natural Products J.-J. Brunet -- Laboratoire de Chimie de Coordination, Toulouse, France Hydroamination of Vinylarenes: Full Regioselectivity Control by the Choice of the Catalyst Alexander Bucka -- Universite de Lausanne, Switzerland Positive Torsional Strain Causes the Formation of a Four-Way Junction at Replication Forks Tailed Duplex DNA Is the Preferred Substrate for Rad51 Protein-Mediated Homologous Pairing Ian S. Butler -- McGill University High-Pressure Study of Ru3(CO)12 by X-ray Diffraction, Raman, and Infrared Spectroscopy Heather G. Calamita -- University of Louisville Control of Autolysis in Bacteria M.J. Calhorda -- University of Lisbon New Model for a Theoretical Density Functional Theory Investigation of the Mechanism of the Carbonic Anhydrase: How Does the Internal Bicarbonate Rearrangement Occur? Group Transfer From Nickel Imido, Phosphinidene, and Carbene Complexes to Ethylene With Formation of Aziridine, Phosphirane, and Cyclopropane Products and Observation of the Enhancement in Enantioselectivity With Conversion for the Aziridination of Styrene Using Copper Bis(oxazoline) Complexes On the Noble Gas-Induced Intersystem Crossing for the CUO Molecule: Experimental and Theoretical Investigations of CUO(Ng)n(Ng = Ar, Kr, Xe; n = 1,2,3,4) Isolation and Ring-Opening of New 1-Sila-3-Metallacyclobutanes (h5-C5bFe) (CO)2CH2 SiR2 Leading to a New Class of Organometallic Polymer New Rhenium(I) Polypyridine Biotin Complexes that Show Luminescence Enhancement and Lifetime Elongation upon Binding to Avidin The First Photocrystallographic Evidence for Light-Induced Metastable Linkage Isomers of Ruthenium Sulfur Dioxide Complexes Effects of the Protein Environment on the Structure and Energetics of Active Sites of Metalloenzymes: ONIOM Study of Methane Monooxygenase and Ribonucleotide Reductase Oligomerization and Cross-Oligomerization of Terminal Alkynes Catalyzed by Organoactinide Complexes Controlling the Catalytic Oligomerization of Terminal Alkynes Promoted by Organoactinides: A Strategy to Short Oligomers Catalytic Hydrosilylation of Terminal Alkynes Promoted by Organoactinides E. Peter M. Candido -- University of British Columbia Activation of a Membrane-Bound Transcription Factor by Regulated Ubiquitin/Proteasome-Dependent Processing Degradation of a Cohesin Subunit by the N-End Rule Pathway Is Essential for Chromosome Stability Hsp26: a Temperature-Regulated Chaperone Greg T. Carroll -- University on Cincinnati Two-Electron Platinum Reagents Nicholas I. Carruthers -- The R. W. Johnson Pharmaceutical Research Institute High-Affinity, Non-Peptide Agonists for the ORL1 (Orphanin FQ/Nociceptin) Receptor Design, Synthesis, and Structure-Activity Relationships of Acetylene-Based Histamine H3 Receptor Antagonists Kendra D. Carter -- Boston University Efficient Activation of Aromatic C-H Bonds for Addition to C-C Multiple Bonds Paulo B. Carvalho -- School of Pharmacy, University of Mississippi Drug Delivery Systems Based on Trimethyl Lock Lactonization: Poly(ethyleneglycol) Prodrugs of Amino-Containing Compounds Giovanni Casiraghi -- Universita del Piemonte Orientale, Novara and Universit a di Parma The Synthesis of the Thapsigargins The Synthesis of the Anti-Malarial Natural Product Polysphorin and Analogues Using Polymer-Supported Reagents and Scavengers Resurrecting the Cornforth Model for Carbonyl Addition: Studies on the Origin of the 1,2-Asymmetric Induction in Enolate Addition to Heteroatom-Substituted Aldehydes Isopavines as a New Class of Morphinomimetics The First Stereoselective Total Synthesis of Quinine The Vinylogous Intramolecular Morita-Baylis-Hillman Reaction Molecular Recognition of Carbonyl Compounds Using Aluminum Tris(2,6-diphenylphenoxide) (ATPH): New Regio- and Stereoselective Alkylation of a,b-Unsaturated Carbonyl Compounds A New Method for the One-Step Synthesis of a,a-Unsaturated Carbonyl Systems from Saturated Alcohols and Carbonyl Compounds The Synthesis of Bisorbicillinoids. An Amazing Self-Assembly of Simple Compounds into Highly Complex Natural Products The Total Synthesis of Frondosin B David F. Cauble Jr. -- University of Texas at Austin The First Direct and Enantioselective Cross-Aldol Reaction of Aldehydes Kenneth G. Caulton -- Indiana University Combined X-Ray Diffraction and Density Functional Study of [Ni(NO)(h5-Cp*)] in the Ground and Light-Induced Metastable States Francesco Cecconi -- University of Tor Vergata, Rome, Italy Distinctive Roles of PHAP Proteins and Prothymosin-Alpha in a Death Regulatory Pathway Albert S.C. Chan -- The Hong Kong Polytechnic University Towards Highly Air-Stable Phosphorus Ligand and Metal-Catalyst Precursors for Cross-Coupling Reactions with Unactivated Aryl Chlorides Philip W. H. Chan -- Tohoku University, Japan The First Novel Direct Oxygen Atom Transfer from Hypervalent Oxido-l3-iodanes to a,b-Unsaturated Carbonyl Compounds to Give a,b-Epoxy Carbonyl Compounds The Direct Catalytic Asymmetric Aldol Reaction Using Rare Earth-Based Heterobi- and Heteropolymetallic BINOL Complexes Brian Chauder -- GlaxoSmithKline Research & Development Development of the First Iminium Catalyzed Enantioselective Friedel-Crafts Reaction: Application to Pyrroles and Indoles Amar Chittiboyina -- University of Mississippi Novel Tricyclic a-Alkoxyphenyl Propanoic Acid Derivatives: Dual PPARa/g Agonists with Hypolipidemic and Antidiabetic Activity Laura Cipolla -- University of Milano-Bicocca Sugar-Derived Amino Acids: Powerful Secondary Structure-Inducing Elements in the Design of Novel Peptidomimetics John D. Cleary -- The Hospital for Sick Children, Toronto, Ontario, Canada, and The University of Toronto The Complex Nature of Trinucleotide Repeat Instability Kevin P. Cole -- The University of Minnesota Synthetic Approaches to Phomactin A James P. Collman -- Stanford University Synthetic Heme Chemistry: The Cradle of Functional Molecules and Catalysts William B. Connick -- University on Cincinnati Two-Electron Platinum Reagents Korey D. Conroy -- Dalhousie University A Simple Resolution Procedure Using the Staudinger Reaction for the Preparation of P-Stereogenic Phosphine Oxides Arthur J. L. Cooper -- Weill Medical College of Cornell University and Burke Medical Research Institute Direct Charging of tRNACUAWith Pyrrolysine In Vitro and In Vivo A New Activity for an Old Enzyme: Escherichia coli Bacterial Alkaline Phosphatase Is a Phosphite-Dependent Hydrogenase Taming of a Poison: Biosynthesis of the NiFe-Hydrogenase Cyanide Ligands Proteins, Peptides and Amino Acids SourceBook Crystal Structure of Histidine Ammonia-Lyase Revealing a Novel Polypeptide Modification as the Catalytic Electrophile Biotin Synthase Contains Two Distinct Iron-Sulfur Cluster Binding Sites: Chemical and Spectroelectrochemical Analysis of Iron-Sulfur Cluster Interconversions A New Model for Protein Stereospecificity Prolyl Hydroxylase, Protein Disulfide Isomerase, and Other Structurally Related Proteins Photoactivated g-Secretase Inhibitors Directed to the Active Site Covalently Label Presenilin 1 Vitamin B6 Biosynthesis: Formation of Pyridoxine 5'-Phosphate from 4-(Phosphohydroxy)-L-threonine and 1-Deoxy-D-xylulose-5-phosphate by PdxA and PdxJ Protein Marco Corvaro -- University of Tor Vergata, Rome, Italy Distinctive Roles of PHAP Proteins and Prothymosin-Alpha in a Death Regulatory Pathway Janine Cossy -- Laboratoire de Chimie Organique, Associe au CNRS, ESPCI, Paris, France Synthesis of Substituted Piperidines via Aziridinium Intermediates: Synthetic Applications Eric D. Coulter -- University of Georgia Bacterial Nonheme Iron Proteins and Oxidative Stress Bacterial Nonheme Iron Proteins and Oxidative Stress Heather A. Coverdale -- University of Minnesota-Twin Cities Recent Synthesis and Applications of Vinamidinium Salts in Alkaloid Chemistry J.A. Cowan -- Ohio State University Cluster-Mediated Conversion of Diphenylacetylene into a-Phenylcinnamaldehyde. Conversion of a Catalytic Hydroformylation Cycle Based on Isolated Intermediates NifS-Directed Assembly of a Transient [2Fe-2S] Cluster within the NifU Protein Alan H. Cowley -- The University of Texas at Austin Stable "Transient" Carbenes Christopher J. Creighton -- The R. W. Johnson Pharmaceutical Research Institute Synthesis of Cyclic Peptides by Ring-Closing Metathesis Alvin L. Crumbliss -- Duke University Kinetics and Mechanism of Axial Ligand Substitution of Alkyl Cobaloximes by Substituted Pyridines in Different Solvents High-Resolution Structure of an Alternate Form of the Ferric Ion Binding Protein from Haemophilus influenzae Can Octahedral t2g6 Complexes Substitute Associatively? The Case of the Isoelectronic Ruthenium(II) and Rhodium(III)Hexaaquaions Electron-Induced Inversion of Helical Chirality in Copper Complexes of N,N-Dialkylmethionines Microbial Iron Transport via a Siderophore Shuttle: A Membrane Ion Transport Paradigm Ascaris Haemoglobin Is a Nitric Oxide-Activated ''Deoxygenase'' Mutations at the Histidine 249 Ligand Profoundly Alter the Spectral and Iron-Binding Properties of Human Serum Transferrin N-Lobe L Mutation of the Iron Ligand His 249 to Glu in the N-Lobe of Human Transferrin Abolishes the Dilysine "Trigger" But Does Not Significantly Affect Iron Release D.P. Curran-- University of Pittsburgh The First Intermolecular Transition Metal-Catalyzed [5 + 2] Cycloadditions with Simple, Unactivated, Vinylcyclopropanes Phase Tagging Strategies for Facile Product Separation in Solution Phase Organic Synthesis J.R. Daban -- Universitat Autónoma de Barcelona Cation-Chromatin Binding as Shown by Ion Microscopy Is Essential for the Structural Integrity of Chromosomes Reversible Hypercondensation and Decondensation of Mitotic Chromosomes Studied Using Combined Chemical-Micromechanical Techniques Mitotic Chromosomes Are Chromatin Networks Without a Mechanically Contiguous Protein Scaffold Cation-Chromatin Binding as Shown by Ion Microscopy Is Essential for the Structural Integrity of Chromosomes Rapid Exchange of Histone H1.1 on Chromatin in Living Human Cells Fast Kinetics of Chromatin Assembly Revealed by Single-Molecule Videomicroscopy and Scanning Force Microscopy Spermidine-Induced Aggregation of Nucleosome Core Particles: Evidence for Multiple Liquid Crystalline Phases Pulling a Single Chromatin Fiber Reveals the Forces That Maintain Its Higher-Order Structure Li-Xin Dai -- Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences A New Principle in Combinatorial Asymmetric Transition-Metal Catalysis: Mixtures of Chiral Monodentate P Ligands Novel Small Organic Molecules for a Highly Enantioselective Direct Aldol Reaction Highly Enantioselective Palladium(II)-Catalyzed Cyclization of (Z)-4--Acetoxy-2--butenyl-2-alkynoates: An Efficient Synthesis of Optically Active g-Butyrolactones Enantioselective Friedel-Crafts Reaction: From Stoichiometric to Catalytic Asymmetric Phase-Transfer Catalysis by a Rigid Quaternary Ammonium Salt S. Dandapani -- University of Pittsburgh Phase Tagging Strategies for Facile Product Separation in Solution Phase Organic Synthesis Gudrun Dandekar -- University of Heidelberg A Receptor Kinase Gene of the LysM Type Is Involved in Legume Perception of Rhizobial Signals A Single Motif Responsible for Ubiquitin Recognition and Monoubiquitination in Endocytic Proteins Thomas Dandekar -- University of Wurzburg A Receptor Kinase Gene of the LysM Type Is Involved in Legume Perception of Rhizobial Signals Targets of the Cyclin-Dependent Kinase Cdk1 A Single Motif Responsible for Ubiquitin Recognition and Monoubiquitination in Endocytic Proteins Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network Complementary Profiling of Gene Expression at the Transcriptome and Proteome Levels in Saccharomycescerevisiae A "Periodic Table" for Protein Structure The Large-Scale Organization of Metabolic Networks The Structural Basis of Ribosome Activity in Peptide Bond Synthesis Stochastic Sensing of Organic Analytes by a Pore-Forming Protein Containing a Molecular Adapter Crystal Structures of the Membrane-Binding C2 Domain of Human Coagulation Factor V Structure of the C2 Domain of Human Factor VIII at 1.5 A Resolution N. D'Angelo -- Stanford University A Facile C-C Bond Cleavage in Epoxides and Its Use for the Synthesis of Oxygenated Heterocycles by a Ring Expansion Strategy Anindya Dasgupta -- University of South Carolina, Columbia Mutations of Glutamate-84 at the Putative Potassium Binding Site Affect Camphor Binding and Oxidation by Cytochrome P450 Falguni Dasgupta -- Chembiotek Research International, Calcutta, India, and Biomarin Pharmaceutical Inc., Novato, CA Novel Synthetic Inhibitors of Selection-Mediated Cell Adhesion: Synthesis of 1,6-Bis [3-(3-carboxy-methylphenyl)-4-(O-a-D-Mannopyranosyl)phenyl] hexane (TBC 1269) Huw M.L. Davies -- University at Buffalo, State University of New York A New Class of Chiral Lewis Acid Catalysts for Highly Enantioselective Hetero-Diels-Alder Reactions: Exceptionally High Turnover Numbers from Dirhodium(II) Carboxamidates John H. Dawson -- University of South Carolina Preparation of Artificial Metalloenzymes by Insertion of Chromium (III) Schiff Base Complexes Into Apomyoglobin Mutants Spectroscopic Characterization and Ligand-Binding Properties of Chlorite Dismutase from the Chlorate Respiring Bacterial Strain GR-1 Effect of Distal Cavity Mutations on the Formation of Compound I in Catalase-Peroxidases Formation and Catalytic Roles of Compound I in the Hydrogen Peroxide-Dependent Oxidations by His 64 Mb Mutants Mutations of Glutamate-84 at the Putative Potassium Binding Site Affect Camphor Binding and Oxidation by Cytochrome P450 The Crystal Structure of Inducible Nitric Oxide Synthase Oxygenase Domain Dimer with L-Arginine and Tetrahydrobiopterin Klaus-Michael Debatin -- University Children's Hospital, Ulm, Germany Death Receptors Brenton DeBoef -- Washington University, Saint Louis C-C Bond Formation via C-H Bond Activation: Synthesis of the Core of Teleocidin B4 Aurelien Deniaud -- Universite de Versailles, St. Quentin, France Cytochrome c Release from Mitochondria: New Rules of the Game Melvin L. DePamphilis -- National Institute of Child Health and Human Development Eukaryotic DNA Replication Origins and the Proteins That Recognize Them Eukaryotic DNA Replication Forks Suman Kumar Dhar -- Special Center for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India Origin Recognition Complex and the Initiation of DNA Replication Suraj Dhungana -- Duke University Can Octahedral t2g6 Complexes Substitute Associatively? The Case of the Isoelectronic Ruthenium(II) and Rhodium(III)Hexaaquaions Microbial Iron Transport via a Siderophore Shuttle: A Membrane Ion Transport Paradigm Mutations at the Histidine 249 Ligand Profoundly Alter the Spectral and Iron-Binding Properties of Human Serum Transferrin N-Lobe L Mutation of the Iron Ligand His 249 to Glu in the N-Lobe of Human Transferrin Abolishes the Dilysine "Trigger" But Does Not Significantly Affect Iron Release Elena Diez -- University of Cambridge, United Kingdom New Strategies for Organic Catalysis: The First Highly Enantioselective Organocatalytic Diels-Alder Reaction Kuiling Ding -- Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences A New Principle in Combinatorial Asymmetric Transition-Metal Catalysis: Mixtures of Chiral Monodentate P Ligands Enantioselective Friedel-Crafts Reaction: From Stoichiometric to Catalytic Marcus Dittrich -- University of Wurzburg Targets of the Cyclin-Dependent Kinase Cdk1 Youngkyu Do -- KAIST, Taejon, Korea Highly Active Iron and Cobalt Catalysts for the Polymerization of Ethylene Remarkably Active Non-Metallocene Ethylene Polymerization Catalysts Monica Donghi -- Department of Chemistry, University of Cambridge, UK Benzotriazoles in Solid-Phase Organic Chemistry David Dolphin -- University of British Columbia Chirality Control of a Cu(I)3(phenanthroline)2 Complex by a Sugar-Boronic Acid Interaction. A Preliminary Step Toward Total Chain Helicity Control by a Chain-End Sugar Binding David M. Dooley -- Montana State University/Bozeman Visualization of Dioxygen Bound to Copper During Enzyme Catalysis Amidation of Bioactive Peptides: The Structure of Peptidylglycine a-Hydroxylating Monooxygenase Trevor Douglas -- Montana State University Phage Display Libraries: A Technique for Peptide-Mineral Discovery Crystal Structure of Naphthalene Dioxygenase: Side-on Binding of Dioxygen to Iron Crystallographic and Spectroscopic Characterization of a Nonheme Fe(IV)=O Complex R.J. Doyle -- University of Louisville Control of Autolysis in Bacteria DNA Damage and Repair: Advances from Phage to Humans, Volume III Yuntao Duan -- University of Rochester Medical Center Gcn4 Activator Targets Gcn5 Histone Acetyltransferase to Specific Promoters Independently of Transcription Bridget R. Duvall -- University of Maryland The Total Synthesis of Proteasome Inhibitors TMC-95A and TMC-95B: Discovery of a New Method to Generate cis-Propenyl Amides Amanda L. Eckermann -- Northwestern University Azidoruthenium(III) Complexes as Precursors for Molecular Nitrogen and Nitrene Complexes Kerrie Nichol Edamura -- The Hospital for Sick Children, Toronto, Ontario, Canada, and The University of Toronto The Complex Nature of Trinucleotide Repeat Instability Bradley O. Elmore -- Montana State University/Bozeman Visualization of Dioxygen Bound to Copper During Enzyme Catalysis Janice P. Evans -- Department of Biochemistry and Molecular Biology, Division of Reproductive Biology, Johns Hopkins University, Bloomberg School of Public Health Getting Sperm and Egg Together: The Molecules of Mammalian Gamete Membrane Interactions P. Andrew Evans -- Indiana University Recent Developments in Rhodium-Catalyzed Allylic Substitution and Carbocyclization Reactions N.T. Fairweather -- University of Pittsburgh The First Intermolecular Transition Metal-Catalyzed [5 + 2] Cycloadditions with Simple, Unactivated, Vinylcyclopropanes Arturo Falaschi -- International Centre for Genetic Engineering and Biotechnology, Trieste, Italy Specification of DNA Replication Origins of Mammalian Genomes Ellen Fanning -- Vanderbilt University Identification of a Binding Region for Human Origin Recognition Complex Proteins 1 and 2 that Coincides with an Origin of DNA Replication Paul L. Feldman -- GlaxoSmithKline Research & Development, Research Triangle Park, NC Discovery and Mechanistic Exploration of a Novel Rhodium-Catalyzed Cyclization Development of the First Iminium Catalyzed Enantioselective Friedel-Crafts Reaction: Application to Pyrroles and Indoles Barbara La Ferla -- University of Milano-Bicocca Sugar-Derived Amino Acids: Powerful Secondary Structure-Inducing Elements in the Design of Novel Peptidomimetics G. Fredrick Filzen -- Pfizer Global Research and Development, Ann Arbor Laboratories Novel Antiarthritic Agents with 1,2-Isothiazolidine-1,1-dioxide (g-Sultam) Skeleton: Cytokine Suppressive Dual Inhibitors of Cyclooxygenase-2 and 5-Lipoxygenase Amethist Shajary Finch -- University of Maryland Resistance to an Herbivore Through Engineered Cyanogenic Glucoside Synthesis Meghan Flaherty -- Duke University Electron-Induced Inversion of Helical Chirality in Copper Complexes of N,N-Dialkylmethionines Patrick T. Flaherty -- University of Kansas The Non-mevalonate Pathway for Isoprenoid Biosynthesis: New Opportunities for Drug Design Ian Fleming -- Cambridge University Improving the Friedel-Crafts Reaction An Enantiomerically Enriched Grignard Reagent Mike Fleming -- Wayne State University Enantioselective Claisen Rearrangements: Development of a First Generation Asymmetric Acyl-Claisen Reaction Michelle Flenniken -- Montana State University Phage Display Libraries: A Technique for Peptide-Mineral Discovery Harvey M. Florman -- Department of Cell Biology, University of Massachusetts Medical School The Acrosome Reaction: An Example of Egg-Activated Signal Transduction in Sperm Rudolf Fluckiger -- Novacule, LLC Brookline, MA Drug Targeting Technology: Physical, Chemical, Biological Methods Daniel L. Flynn -- Neogenesis Pharmaceuticals, Inc. Natural Product Synthesis Utilizing Solid-Supported Reagents Eleonora Forni -- University of Milano-Bicocca Sugar-Derived Amino Acids: Powerful Secondary Structure-Inducing Elements in the Design of Novel Peptidomimetics Matthew W. Foster -- Ohio State University NifS-Directed Assembly of a Transient [2Fe-2S] Cluster within the NifU Protein Brian R. Francis -- University of Wyoming A Hypothesis that Ribosomal Protein Synthesis Evolved from Coupled Protein and Nucleic Acid Synthesis Doug Frantz -- Merck & Co., Inc. Thiazolium-Catalyzed Cross-Coupling of Aldehydes with Acylimines: A New Method for the Synthesis of a-Amidoketones Simone Fulda -- University Children's Hospital, Ulm, Germany Death Receptors Alois Furstner -- Max-Planck-Institut fur Kohlenforschung, Mulheim/Ruhr, Germany Platinum-Catalyzed Skeletal Rearrangement Reactions: Generating Structural Diversity by a Uniform Mechanism Hans-Joachim Gabius -- Ludwig-Maximilians-University Munich Handbook of Animal Lectins: Properties and Biomedical Applications PCR Cloning Protocols, 2nd Edition: Methods in Molecular Biology, Volume 192 Insights into the Molecular Basis of Leukocyte Tethering and Rolling Revealed by Structures of P- and E-Selectin Bound to SLex and PSGL-1 Galectin-1 Binds Oncogenic H-Ras to Mediate Ras Membrane Anchorage and Cell Transformation On the Meaning of Affinity: Cluster Glycoside Effects and Concanavalin A Christopher J. Gabriel -- The Ohio State University Developments in Fluorous Mitsunobu Chemistry F. Gallou -- The Ohio State University [6p + 2p] and [6p + 4p] Higher-Order Cycloadditions and Their Deployment in Total Synthesis Carmen Garrido -- INSERM U517, Faculty of Medicine, Dijon, France Smac Agonists Sensitize for Apo2L/TRAIL- or Anticancer Drug-Induced Apoptosis and Induce Regression of Malignant Glioma In Vivo Sanjay Gayakwad -- University Of Maryland Ketopremithramycins and Ketomithramycins, Four New Aureolic Acid-Type Compounds Obtained upon Inactivation of Two Genes Involved in the Biosynthesis of the Deoxysugar Moieties of the Antitumor Drug Mithramycin by Streptomyces argillaceus, Reveal Novel Insights into Post-PKS Tailoring Steps of the Mithramycin Biosynthetic Pathway Gunda I. Georg -- University of Kansas Stereoselective Syntheses of Epothilones A and B via Nitrile Oxide Cycloadditions An Efficient Gram-Scale Synthesis of (+)-Discodermolide The Non-mevalonate Pathway for Isoprenoid Biosynthesis: New Opportunities for Drug Design Andrew G. Geyer -- Pfizer Global Research and Development, Ann Arbor Laboratories Novel Antiarthritic Agents with 1,2-Isothiazolidine-1,1-dioxide (g-Sultam) Skeleton: Cytokine Suppressive Dual Inhibitors of Cyclooxygenase-2 and 5-Lipoxygenase Giuliano Giambastiani -- ICCOM-CNR, Florence, Italy ''Oscillating'' Metallocene Catalysts: How Do They Oscillate? Continuous Flow Homogeneous Catalysis: Hydroformylation of Alkenes in Supercritical Fluid-Ionic Liquid Biphasic Mixtures Supported Ionic Liquid Catalysis-A New Concept for Homogeneous Hydroformylation Catalysis High-Activity, Single-Site Catalyst for the Alternating Copolymerization of CO2 and Propylene Oxide Fluorous Biphasic Catalysis Without Perfluorinated Solvents: Application to Pd-Mediated Suzuki and Sonogashira Couplings On the Origin of Opposite Stereoselection in the Asymmetric Hydrogenation of Phenyl-and tert-Butyl-Substituted Enamides Asymmetric Hydrogenation of Enamides with Rh-BisP and Rh-MiniPHOS Catalysts: Scope, Limitations, and Mechanism Palladium-Catalyzed Arylation of Malonates and Cyanoesters Using Sterically Hindered Trialkyl-and Ferrocenyldialkylphosphine Ligands A General and Mild Copper-Catalyzed Arylation of Diethyl Malonate Asymmetric Catalysis with the Normally Unresolvable, Conformationally Dynamic 2,2¢-Bis(diphenylphosphino)-1,1¢-biphenyl (Biphep) Resolution of Pd Catalyst with tropos Biphenylphosphine (BIPHEP) Ligand by DM-DABN: Asymmetric Catalysis by an Enantiopure BIPHEP-Pd Complex Asymmetric Activation of the Pd Catalyst Bearing the tropos Biphenylphosphine (BIPHEP) Ligand with the Chiral Diaminobinaphthyl (DABN) Activator The First Example of Palladium Catalysed Non-perfectly Alternating Copolymerisation of Ethene and Carbon Monoxide Discovery of Exceptionally Efficient Catalysts for Solvent-Free Enantioselective Hetero-Diels-Alder Reaction Regio- and Stereo-Control in Rhodium-Catalyzed Allylic Substitutions Nathan C. Gianneschi-- Northwestern University The Sliding Torus: Catalytic Molecular Rings as Mimics for Natural Processive Enzymes Resorcarene-Based Nanoarchitectures Brian R. Gibney -- Columbia University Ferredoxin and Ferredoxin-Heme Maquettes* Proton Coupling to [4Fe-4S]2+/+ and [4Fe-4Se]2+/+ Oxidation/Reduction in a Designed Protein Scott R. Gilbertson -- Washington University, Saint Louis C-C Bond Formation via C-H Bond Activation: Synthesis of the Core of Teleocidin B4 Parallel and Rational Approaches to Catalyst Development A Novel Peptide-Based Encoding System for "One-Bead One-Compound" Peptidomimetic and Small Molecule Combinatorial Libraries Reaction Microarrays: A Method for Rapidly determining the Enantionmeric Excess of Thousands of Samples High-Yielding Staudinger Ligation of Phosphinoesters and Azides to Form Amides Wayne L. Gladfelter -- University of Minnesota Cubic Hybrid Organic­Inorganic Mesoporous Crystal with a Decaoctahedral Shape Rainer Glaser -- University of Missouri-Columbia Polar Order in Crystalline Molecular Organic Materials by Rational Design Hilary A. Godwin -- Northwestern University The ATP Hydrolytic Activity of Purified ZntA, a Pb(II)/Cd(II)/Zn(II)-Translocating ATPase from Escherichia coli Joel M. Gottesfeld -- The Scripps Research Institute, La Jolla, California Regulation of Gene Expression with Synthetic DNA-Binding Ligands Edward J.J. Grabowski -- Merck & Co., Inc. Thiazolium-Catalyzed Cross-Coupling of Aldehydes with Acylimines: A New Method for the Synthesis of a-Amidoketones Vijaya Gracias -- Abbott Laboratories Asymmetric Total Synthesis of (+)-Sparteine and the Synthesis of a Readily Accessible (+)-Sparteine Surrogate Brian Lawrence Gray -- University of Cambridge Evolving Cascades: The Claisen Rearrangement in the Development of Tandem Sequences of Three or More Reactions Harry B. Gray -- Beckman Institute, California Institute of Technology Carbonyl Derivatives of Chloride­Dimethyl Sulfoxide-Ruthenium(III) Complexes: Synthesis, Crystal Structure, and Reactivity of s[(DMSO)2H][trans-RuCl4(DMSO)(CO)] and [mer,cis-RuCl 3(DMSO)2(CO)] Nora S. Green -- University of California, Los Angeles Evaluation of Isoprenoid Conformation in Solution and in the Active Site of Protein-Farnesyl Transferase Using Carbon-13 Labeling in Conjunction with Solution- and Solid-State NMR Structures of Enzymes Involved in Terpenoid Biosynthesis Philip D. Gregory -- Sangamo BioSciences Global Histone Acetylation and Deacetylation in Yeast Cynthia J. Guidi -- University of Massachusetts Medical School, Worcester Ini1 Is Essential for Embryonic Development and Tumor Suppression Anton B. Guliaev -- University of California, Berkeley Molecular Basis for Discriminating Between Normal and Damaged Bases by the Human Alkyladenine Glycosylase, AAG Hong-Chao Guo -- Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences A New Principle in Combinatorial Asymmetric Transition-Metal Catalysis: Mixtures of Chiral Monodentate P Ligands Jorg Habermann -- Department of Chemistry, University of Cambridge, UK Benzotriazoles in Solid-Phase Organic Chemistry The Bestmann Ylide as a Multi-Purpose Wittig Reagent Michael E. Hagerman -- Union College Magnesium Manganese Oxide Nanoribbons: Synthesis, Characterization, and Catalytic Application Layered Nanocomposites of Aggregated Dyes and Inorganic Scaffolding Synthesis of Hydrophobic Molecular Sieves by Hydrothermal Treatment with Acetic Acid Arnar Halldorsson -- University of Iceland and Dalhousie University Asymmetric Pauson-Khand Reactions Using Camphor-Derived Chelating Thiols as Chiral Controllers Bo Hang -- University of California, Berkeley Human Thymine DNA Glycosylase (TDG) and Methyl-CpG-Binding Protein 4 (MBD4) Excise Thymine Glycol (Tg) from a Tg:G Mispair The Main Role of Human Thymine-DNA Glycosylase Is Removal of Thymine Produced by Deamination of 5-Methylcytosine and Not Removal of Ethenocytosine Investigation of the Substrate Spectrum of the Human Mismatch-Specific DNA N-Glycosylase MED1 (MBD4): Fundamental Role of the Catalytic Domain Biphasic Kinetics of the Human DNA Repair Protein MED1 (MBD4), a Mismatch-Specific DNA N-Glycosylase Paul R. Hanson -- University of Kansas Hypervalent Iodine-Promoted Phenolic Oxidations: Generation of a Highly Versatile o-Quinone Template Natural Product Synthesis Utilizing Solid-Supported Reagents The Three-Component Boronic Acid Mannich Reaction: Structural Diversity and Stereoselectivity Michael Harmata -- University of Missouri-Columbia The Nazarov Reaction: Substituent Effects, Catalysis and Asymmetric Catalysis Electron Transfer Initiated Cyclization (ETIC) Bissulfoximine Ligands in Asymmetric Synthesis Stereoselective Preparation of (Z)-2-(Trialkylsilyloxy)-2-alkenals by Retrocycloaddition Reactions of 4H-4-Alkyl-5-(trialkylsilyloxy)-1,3-dioxins. Useful Reactants for Lewis Acid-Catalyzed [4 + 3] Cyclizations Andrew M. Harned -- University of Kansas Natural Product Synthesis Utilizing Solid-Supported Reagents Todd C. Harrop -- University of California, Santa Cruz New Colorimetric Detection of Glucose by Means of Electron-Accepting Indicators: Ligand Substitution of [Fe(acac)3-n(phen)n]n+ Complexes Triggered by Electron Transfer from Glucose Oxidase Novel Zinc Fluorescent Probes Excitable with Visible Light for Biological Applications Highly Zinc-Selective Fluorescent Sensor Molecules Suitable for Biological Applications Ryan Hartung -- The Ohio State University Recent Synthetic Applications of the Tandem Staudinger/Aza-Wittig Reaction New Synthetic Tactics Designed to Access Diynes and Polyynes Matthew D. Havighurst -- Colorado State University Quantum Chemical Calculations and Experimental Evidence for O-Bonding of Carbon Monoxide to Alkali Metal Cations in Zeolites Infrared Spectra and Density Functional Calculations for OMCO, OM-(h2-CO), OMCO+, and OMOC+(m D V, Ti) in Solid Argon Ronald T. Hay -- University of St. Andrews, St. Andrews, Scotland Ubiquitin and Ubiquitin-like Modifiers: Conserved Mechanisms and Diverse Functions Jeffrey J. Hayes -- University of Rochester Medical Center Methylation of Histone H3 by COMPASS Requires Ubiquitination of Histone H2B by Rad6 Methyltransferase Recruitment and DNA Hypermethylation of Target Promoters by an Oncogenic Transcription Factor Gcn4 Activator Targets Gcn5 Histone Acetyltransferase to Specific Promoters Independently of Transcription Activator-Dependent Transcription from Chromatin In Vitro Involving Targeted Histone Acetylation by p300 Accessibility of Nucleosomal DNA to V(D)J Cleavage Is Modulated by RSS Positioning and HMG 1 Accessibility of Nucleosomal DNA to V(D)J Cleavage Is Modulated by RSS Positioning and HMG 1 Eric Hébert -- Centre de Biophysique Moléculaire, CNRS, Orleans, France Galectin-3 Control of Cell Growth and Death John T. Henri -- University of Kansas An Efficient Gram-Scale Synthesis of (+)-Discodermolide Mark J. Henson -- Stanford University Crystal Structure of a Plant Catechol Oxidase Containing a Dicopper Center Wolfgang A. Herrmann -- Anorganisch-chemisches Institut der Technischen Universitat Munchen, Germany Methyltrioxorhenium Jared J. Heymann -- Duke University Kinetics and Mechanism of Axial Ligand Substitution of Alkyl Cobaloximes by Substituted Pyridines in Different Solvents Karrie A. Hines -- University of Iowa Deciphering the Code of Silence: Mechanisms of Gene Repression With Connections to Human Disease Jerald C. Hinshaw -- The University of Utah Pursuit of Optimal Carbohydrate-Based Anticancer Vaccines: Preparation of a Multiantigenic Unimolecular Glycopeptide Containing the Tn, MBrl, and LewisY Antigens The Design, Synthesis, and Evaluation of Molecules that Enable or Enhance Cellular Uptake: Peptoid Molecular Transporters Amanda L. Hofacker -- The Ohio State University Rhodium Catalyzed Ortho-Alkylation of Aromatic Aldimines and Ketimines with Olefins via C-H Bond Activation Jeff A. Hoffman -- Union College Synthesis of Hydrophobic Molecular Sieves by Hydrothermal Treatment with Acetic Acid Robert V. Hoffman -- New Mexico State University Catalysts, Anticatalysts, and Receptors for Unactivated Phosphate Diesters in Water The Steric Course of SE Reactions of Unstabilized a-Aminoorganolithiums: Distinguishing Between SET and Polar Mechanisms Asymmetric Synthesis of Chiral Organofluorine Compounds: Use of Nonracemic Fluoroiodoacetic Acid as a Practical Electrophile and Its Application to the Synthesis of Monofluoro Hydroxyethylene Dipeptide Isosteres within a Novel Series of HIV Protease Inhibitors Catalytic in Situ Generation of Zn(II)-Alkynilides under Mild Conditions: A Novel CDN Addition Process Utilizing Terminal Acetylenes Facile Enantioselective Synthesis of Propargylic Alcohols by Direct Addition of Terminal Alkynes to Aldehydes Two Classes of Enzymes of Opposite Stereochemistry in an Organism: One for Fluorinated and Another for Nonfluorinated Substrates Daniel D. Holsworth -- Pfizer, Ann Arbor Laboratories Molecular Properties That Influence the Oral Bioavailability of Drug Candidates A Model for Predicting Likely Sites of CYP3A4-Mediated Metabolism on Drug-like Molecules Pyrazole Urea-Based Inhibitors of p38 MAP Kinase: From Lead Compound to Clinical Candidate Richard C. Holz -- Utah State University The CuA Center of Soulble Domain from Thermus Cytochrome ba3. An NMR Investigation of the Paramagnetic Protein A Proton NMR Study of the Paramagnetic Active Site of the CuA Variant of Amicyanin Richard J. Hooley -- Princeton University A Quest for Better Substrates and Catalysts in Arylation Reactions: Iron-Catalyzed Cross-Coupling of Grignard Reagents with Aryl Chlorides, Tosylates, and Triflates Dieter Hoppe -- Westfalische Wilhelms-Universit at Munster, Germany Stereospecific Preparation of Highly Enantiomerically Enriched Organomagnesium Reagents K.N. Houk -- University of California, Los Angeles An Unexpected Bispericyclic Transition Structure Leading to 4 + 2 and 2 + 4 Cycloadducts in the Endo Dimerization of Cyclopentadiene The First Optically Active BINOL-BINAP Copolymer Catalyst: Highly Stereoselective Tandem Asymmetric Reactions Evaluation of Isoprenoid Conformation in Solution and in the Active Site of Protein-Farnesyl Transferase Using Carbon-13 Labeling in Conjunction with Solution- and Solid-State NMR Structures of Enzymes Involved in Terpenoid Biosynthesis Proline-Catalyzed Direct Asymmetric Aldol Reactions Catalytic Asymmetric Synthesis of anti-1,2-Diols Elizabeth A. Howes -- Gamete Signalling Laboratory, The Babraham Institute, Cambridge, UK Secondary Binding of Mammalian Sperm to the Egg Zona Pellucida Y. Hsiao -- Merck & Co., Inc. Hydrogenation of Carbon Dioxide Catalyzed by Ruthenium Trimethylphosphine Complexes: The Accelerating Effect of Certain Alcohols and Amines Richard P. Hsung -- University of Minnesota-Twin Cities Syntheses and Stereoselective 1,2-Addition Reactions of Chiral Stannyl Allenamides Transition Metal-Catalyzed [2 + 2 + 2] Cycloadditions With Ynamides Recent Synthesis and Applications of Vinamidinium Salts in Alkaloid Chemistry Synthetic Approaches to Phomactin A Recent Approaches to cis-Azadecalins: Synthesis of Dendrobatid Alkaloid Pumiliotoxin C Lain-Yen Hu -- Pfizer, Ann Arbor Laboratories Molecular Properties That Influence the Oral Bioavailability of Drug Candidates Ryan R. Huddleston -- University of Texas at Austin Nucleophilic Activation of Enones via Homogeneous Catalytic Hydrogenation: Catalytic Reductive C-C Bond Formation Under Hydrogenation Conditions Chambers C. Hughes -- University of California, Berkeley Direct Catalytic Asymmetric Amination of Aldehydes: Synthesis of Evans Oxazolidinones and a-Amino Acids Jamie M. Iannacone -- Union College Layered Nanocomposites of Aggregated Dyes and Inorganic Scaffolding T. Ikeno -- Keio University Chiral Brønsted Acid-Catalyzed Mannich-Type Reaction Anthony N. Imbalzano -- University of Massachusetts Medical School, Worcester Ini1 Is Essential for Embryonic Development and Tumor Suppression Axel Imhof -- Adolf-Butenandt Institute, University of Munich Transitions in Distinct Histone H3 Methylation Patterns at the Heterochromatin Domain Boundaries Yukio Ishimi -- Mitsubishi Kagaku Institute of Life Sciences Cyclin-Dependent Kinases Prevent DNA Rereplication through Multiple Mechanisms Rajesh Iyengar -- Abbott Laboratories Asymmetric Total Synthesis of (+)-Sparteine and the Synthesis of a Readily Accessible (+)-Sparteine Surrogate Oxaziridines as N- and O-Functionalization Reagents Mehran Jalaie -- Pfizer Global Research and Development A Model for Predicting Likely Sites of CYP3A4-Mediated Metabolism on Drug-like Molecules Hye-Young Jang -- University of Texas at Austin Nucleophilic Activation of Enones via Homogeneous Catalytic Hydrogenation: Catalytic Reductive C-C Bond Formation Under Hydrogenation Conditions Noble Jarrell -- University of Maryland New Stereoselective Method for Carotenoid Synthesis Bruce B. Jarvis -- University Of Maryland Ketopremithramycins and Ketomithramycins, Four New Aureolic Acid-Type Compounds Obtained upon Inactivation of Two Genes Involved in the Biosynthesis of the Deoxysugar Moieties of the Antitumor Drug Mithramycin by Streptomyces argillaceus, Reveal Novel Insights into Post-PKS Tailoring Steps of the Mithramycin Biosynthetic Pathway A Novel Biosynthetic Pathway Providing Precursors for Fatty Acid Biosynthesis and Secondary Metabolite Formation in Myxobacteria Resistance to an Herbivore Through Engineered Cyanogenic Glucoside Synthesis Halipeptins A and B: Two Novel Potent Anti-inflammatory Cyclic Depsipeptides from the Vanuatu Marine Sponge Haliclona Species Haouamines A and B: A New Class of Alkaloids from the Ascidian Aplidium haouarianum Total Synthesis of (S)-(+)-Citreofuran by Ring-Closing Alkyne Metathesis Borogol A: A Linear Cationic Peptide Antibiotic Produced by a Marine Microorganism New Approach to Multiply Deuterated Isoprenoids Using Triply Engineered Escherichia coli and Its Potential as a Tool for Mechanistic Enzymology Design and Synthesis of Pyrrolidine-5,5-trans-lactams as Novel Mechanism Based Inhibitors of Human Cytomegalovirus Protease The Total Synthesis of Proteasome Inhibitors TMC-95A and TMC-95B: Discovery of a New Method to Generate cis-Propenyl Amides Total Synthesis of Nominal Diazonamides. Part 1: Convergent Preparation of the Structure Proposed for (-)-Diazonamide A. Part 2: On the True Structure and Origin of Natural Isolates Novel Natural Products from Soil DNA Libraries in a Streptomycete Host Alternative Modular Polyketide Synthase Expression Controls Macrolactone Structure Biosynthesis of Complex Polyketides in a Metabolically Engineered Strain of E. coli New Stereoselective Method for Carotenoid Synthesis Metabolism of the Host-Selective Toxins Destruxin B and Homodestruxin B: Probing a Plant Disease Resistance Trait Theresa L. Johnson -- University of Mississippi Structural Specificity of Chloroquine-Hematin Binding Related to Inhibition of Hematin Polymerization and Parasite Growth Roy Jones -- Gamete Signalling Laboratory, The Babraham Institute, Cambridge, UK Secondary Binding of Mammalian Sperm to the Egg Zona Pellucida Stephen N. Jones -- University of Massachusetts Medical School, Worcester Ini1 Is Essential for Embryonic Development and Tumor Suppression Albert Jordan -- Gladstone Institute of Virology and Immunology, University of California, San Francisco Towards a Molecular Understanding of the Silencing of Transcription by Heterochromatin: Methylation of Histone H3 Lysine 9 Creates a Binding Site for HP1 Proteins Selective Recognition of Methylated Lysine 9 on Histone H3 by the HP1 Chromo Domain Role of Histone H3 Lysine 9 Methylation in Epigenetic Control of Heterochromatin Assembly Luca Jovine -- Mount Sinai School of Medicine Effector Sites in the Three-Dimensional Structure of Mammalian Sperm b-Acrosin Weston R. Judd -- University of Kansas Total Syntheses of Martinella Alkaloids Hershel Jude -- University on Cincinnati Two-Electron Platinum Reagents Melissa K. Jungnickel -- Department of Cell Biology, University of Massachusetts Medical School The Acrosome Reaction: An Example of Egg-Activated Signal Transduction in Sperm Allurin, a 21-kDa Sperm Chemoattractant from Xenopus Egg Jelly, Is Related to Mammalian Sperm-Binding Proteins Herbert Kaltner -- Ludwig-Maximilians-University, Munich PCR Cloning Protocols, 2nd Edition: Methods in Molecular Biology, Volume 192 Elizabeth F. Karan -- University of Rochester Redox Thermodynamics of Low-Potential Iron-Sulfur Proteins Hui-I Kao -- University of Rochester School of Medicine and Dentistry RPA Governs Endonuclease Switching During Processing of Okazaki Fragments in Eukaryotes Mark S. Kaucher -- University of Maryland Haouamines A and B: A New Class of Alkaloids from the Ascidian Aplidium haouarianum Steven W. Keller -- University of Missouri-Columbia Cooperative Guest Inclusion by a Zeolite Analogue Coordination Polymer: Sorption Behavior with Gases and Amine and Group I Metal Salts Jason A. Kellogg -- University of Rochester Heme Ligation and Conformational Plasticity in the Isolated c Domain of Cytochrome cd1 Nitrite Reductase Heme Ligation and Conformational Plasticity in the Isolated c Domain of Cytochrome cd1 NitriteReductase Richard M. Kellogg -- Syncom B.V. Aerobic Ruthenium-Catalyzed Oxidative Cyanation of Tertiary Amines With Sodium Cyanide Direct Substitution of the Hydroxy Group in Alcohols With Silyl Nucleophiles Catalyzed by Indium Trichloride Highly Efficient Addition of Activated Methylene Compounds to Alkenes Catalyzed by Gold and Silver Synthesis and Reactions of (2,2,2-Trifluoroethyl)triphenylphosphonium Trifluoromethanesulfonate Transition-Metal-Free Suzuki-Type Coupling Reactions One-Step Stereocontrol of Three Contiguous Stereogenic Centers in Acyclic Systems: The Tuning Effect of an Additive in a Tandem Asymmetric Michael Addition and Meerwein-Ponndorf-Verley Reduction A Synthesis of Sumanene, a Fullerene Fragment Recent Developments on the Use of Gallium Halides in Organic Synthesis Enantioselective Catalysis of Photochemically Induced Cycloadditions Synthesis of 2,6-Bridged Piperazine-3-ones by N-Acyliminium Ion Chemistry Enantioconvergent Synthesis by Sequential Asymmetric Horner-Wadsworth-Emmons and Palladium-Catalyzed Allylic Substitution Reactions On the Use of Phosphine-Free PdCl2(SEt2)2 Complex as Catalyst Precursor for the Heck Reaction Iridium Catalysts for the Borylation of Aromatics Synthesis of Furoquinolines by a Multicomponent Domino Process Enantioselective Synthesis of Unsaturated Cyclic Tertiary Ethers by Mo-Catalyzed Olefin Metathesis Ti(II)-Mediated Tandem Inter- and Intramolecular Coupling Reaction of Unsaturated Hydrocarbons: One-Pot Preparation of Cyclopentanes and Cyclohexanes from Readily Available Acyclic Starting Materials A Polymer-Supported Thionating Reagent Palladium Complex Catalyzed Acylation of Allylic Esters with Acylsilanes Facile Synthesis of Acylsilanes via Aerobic Oxidation of gem-Disilylalkylcopper Compounds Preparation of Desymmetrized Meso-Tartrate Derivatives: Synthesis and Utility of (R0,R0,R,S)-2,3-Butane Diacetal Protected Dimethyl Tartrate Molecular-Sieve Catalysts for the Selective Oxidation of Linear Alkanes by Molecular Oxygen Nickel on Charcoal (''Ni/C''): An Expedient and Inexpensive Heterogeneous Catalyst for Cross-Couplings Between Aryl Chlorides and Organometallics. I. Functionalized Organozinc Reagents Neutral, Single-Component Nickel(II) Polyolefin Catalysts that Tolerate Heteroatoms A Practical Method for Alcohol Oxidation with Aqueous Hydrogen Peroxide under Organic Solvent-and Halide-Free Conditions Nickel on Charcoal (''Ni/C''): An Expedient and Inexpensive Heterogeneous Catalyst for Cross-Couplings Between Aryl Chlorides and Organometallics. I. Functionalized Organozinc Reagents Rhodium(I)-Catalyzed Asymmetric Intramolecular Pauson-Khand-Type Reaction Highly Selective Palladium-Catalyzed Synthesis of Protected a,b-Unsaturated Methyl Ketones and 2-Alkoxy-1,3-butadienes: High-Speed Chemistry by Microwave Flash Heating Joseph L. Kent -- University of Pittsburgh A Novel Application of a Pd(0)-Catalyzed Nucleophilic Substitution Reaction to the Regio- and Stereoselective Synthesis of Lactam Analogues of the Epothilone Natural Products A. Kerman -- McMaster University, Hamilton, Ontario Polar Residues Drive the Association of Polyleucine Transmembrane Helices Frederick Khachik -- University of Maryland New Stereoselective Method for Carotenoid Synthesis Youngjo Kim -- KAIST, Taejon, Korea Highly Active Iron and Cobalt Catalysts for the Polymerization of Ethylene Remarkably Active Non-Metallocene Ethylene Polymerization Catalysts Irah King -- University of Rochester Medical Center Methyltransferase Recruitment and DNA Hypermethylation of Target Promoters by an Oncogenic Transcription Factor Jackson C. Kirkman-Brown -- Department of Cell Biology, University of Massachusetts Medical School The Acrosome Reaction: An Example of Egg-Activated Signal Transduction in Sperm Lorrie A. Kirshenbaum -- St. Boniface General Hospital Research Centre and University of Manitoba, Winnipeg, Manitoba, Canada A Novel Role for the Mitochondrial Death Proteins Nix and BNIP3 in Cardiac Cell Death and Heart Failure Carolyn M. Klinge -- University of Louisville School of Medicine Estrogen Response Element Sequence as an Allosteric Regulator of Estrogen Receptor Action Susanne Kneitz -- University of Wurzburg Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network Complementary Profiling of Gene Expression at the Transcriptome and Proteome Levels in Saccharomycescerevisiae Nathan Knotts -- University of Missouri-Columbia Polar Order in Crystalline Molecular Organic Materials by Rational Design Shu Kobayashi -- Graduate School of Pharmaceutical Sciences, The University of Tokyo, and CREST, Japan Science and Technology Corporation (JST) Palladium-Catalyzed Direct Transformation of Carboxylic Acids to Aldehydes and Ketones Ethenylation of Silyl Enol Ethers with Silylethyne Joseph W. Kolis -- Clemson University Anisotropic Templating Effect in the Formation of Two-Dimensional Anionic Cadmium­Thiocya-nate Coordination Solids [(12C4)2Cd][Cd22(SCN)6] and [(12C4)2Cd][Cd3(SCN)8] with Check-erboard and Herringbone Patterns Respectively Inorganic Linkage Isomerism in the Thiocyanate Ligand Nenad M. Kostic -- Iowa State University Synthesis and Structure of Formally Hexavalent Palladium Complexes Hexakis(silyl)palladium(VI) or Palladium(II) with NNN2-Disilane Ligands? Electronic Structure and Bonding in Hexacoordinate Silyl-Palladium Complexes David Kowalski -- Roswell Park Cancer Institute Checkpoint Kinase Proteins Stabilize DNA Replication Forks After DNA Damage or Arrest of Fork Movement A.J. Kresge -- University of Toronto Comparison of Activation Parameters for Ionization Reactions Within Zeolites and in Aqueous Methanol Solution The Crystal Structure of a Simple Enol Formed in a Single-Crystal-to-Single-Crystal Enolene Rearrangement Wolff Rearrangement of 2-Diazo-1(2H)-Naphthalenone Induced by Nonresonant Two-Photon Absorption of NIR Radiation The Photochemical Wolff Rearrangement of 3-Diazo-1,1,1-trifluoro-2-propanone Revisited Photochemical Generation and Absolute Reactivity of an Allene Oxide in Solution Comparison of a Protonated Quinone Methide and a Methoxybenzyl Carbocation Analog Migration of Methyl Groups Between Aliphatic Amines in Water Preparation of the Tricyclo[5.3.1.13,9]dodeca-1,5-diyl Dication: Attempts to Prepare a Novel m-H Cation Contribution of Phosphate Intrinsic Binding Energy to the Enzymatic Rate Acceleration of Triosephosphate Isomerase Mode of Action of Carcinogenic Aromatic Amines Keto-Enol Tautomerism of Phenols in Aqueous Solution Bridgehead Carbocations via Carbene Fragmentation: Erasing a 1010 Kinetic Preference At Last, 1,10-Phenanthroline-N,N0 -dioxide, a New Type of Helicene, Has Been Synthesized Using HOF3CN Hepta- and Octanitrocubane Teaching Old Indicators New Tricks: A Colorimetric Chemosensing Ensemble for Tartrate/Malate in Beverages Femtosecond Dynamics of Norrish Type-II Reactions: Nonconcerted Hydrogen-Transfer and Diradical Intermediacy Michael J. Krische -- University of Texas at Austin Nucleophilic Activation of Enones via Homogeneous Catalytic Hydrogenation: Catalytic Reductive C-C Bond Formation Under Hydrogenation Conditions The First Direct and Enantioselective Cross-Aldol Reaction of Aldehydes Second Generation Light-Driven Molecular Motors: Unidirectional Rotation Controlled by a Single Stereogenic Center with Near-Perfect Photoequilibria and Acceleration of the Speed of Rotation by Structural Modification Guido Kroemer -- Centre National de la Recherche Scientifique, Villejuif, France Mitochondria in Apoptosis: The Suicide Organelles Jennifer L. Kuebler -- University of Maryland Total Synthesis of (S)-(+)-Citreofuran by Ring-Closing Alkyne Metathesis Fritz E. Kuhn -- Anorganisch-chemisches Institut der Technischen Universitat Munchen, Germany Methyltrioxorhenium Rajeev Kumar -- RWTH Aachen, Aachen, Germany Bridging Traditional Medicines with Modern Biotechnology G. Ravi Kumar -- RWTH Aachen, Aachen, Germany Bridging Traditional Medicines with Modern Biotechnology Kousik Kundu -- University of Maryland New Approach to Multiply Deuterated Isoprenoids Using Triply Engineered Escherichia coli and Its Potential as a Tool for Mechanistic Enzymology Min-Hao Kuo -- Michigan State University Tackling the Chromatin Dynamics: Use of Antibodies Against Acetylated Histones and Other Vibrant Chromatin Features Donald M. Kurtz Jr. -- University of Georgia Nickel Superoxide Dismutase Structure and Mechanism Crystal Structure of Nickel-Containing Superoxide Dismutase Reveals Another Type of Active Site Bacterial Nonheme Iron Proteins and Oxidative Stress Tuning the Electronic Structure of Octahedral Iron Complexes {FeL-X-}(L = 1-Alkyl-4,7-bis(4-tert-butyl-2-mercaptobenzyl)-1,4,7-triazacyclononane, X = Cl, CH3O, CN, NO): The S = 1/2 Ü S = 3/2 Spin Equilibrium of {FeLPr(NO)} High-Resolution Crystal Structures and Spectroscopy of Native and Compound I Cytochrome c Peroxidase Bacterial Nonheme Iron Proteins and Oxidative Stress Germin Is a Manganese Containing Homohexamer with Oxalate Oxidase and Superoxide Dismutase Activities A Biological Function for Cadmium in Marine Diatoms Steady-State and Transient Kinetics of Escherichia coli Nitric Oxide Dioxygenase (Flavohemoglobin) Jason Lagona -- University of Maryland Borogol A: A Linear Cationic Peptide Antibiotic Produced by a Marine Microorganism Robert S. Lahue -- University of Nebraska Medical Center DNA Mismatch Repair and Trinucleotide Repeat Instability: the Expansion Connection Andrew G. Leach -- University of California, Los Angeles An Unexpected Bispericyclic Transition Structure Leading to 4 + 2 and 2 + 4 Cycloadducts in the Endo Dimerization of Cyclopentadiene The First Optically Active BINOL-BINAP Copolymer Catalyst: Highly Stereoselective Tandem Asymmetric Reactions David K. Leahy -- Indiana University Recent Developments in Rhodium-Catalyzed Allylic Substitution and Carbocyclization Reactions J.P. Leal -- Instituto Tecnologico e Nuclear Oligomerization and Cross-Oligomerization of Terminal Alkynes Catalyzed by Organoactinide Complexes Controlling the Catalytic Oligomerization of Terminal Alkynes Promoted by Organoactinides: A Strategy to Short Oligomers Catalytic Hydrosilylation of Terminal Alkynes Promoted by Organoactinides Amy P. Ledbetter -- University of South Carolina The Crystal Structure of Inducible Nitric Oxide Synthase Oxygenase Domain Dimer with L-Arginine and Tetrahydrobiopterin Chulbom Lee -- Princeton University A Quest for Better Substrates and Catalysts in Arylation Reactions: Iron-Catalyzed Cross-Coupling of Grignard Reagents with Aryl Chlorides, Tosylates, and Triflates Min Hyung Lee -- KAIST, Taejon, Korea Highly Active Iron and Cobalt Catalysts for the Polymerization of Ethylene Remarkably Active Non-Metallocene Ethylene Polymerization Catalysts Brian J. Lemon -- Utah State University Crystal Structure of a Carbon Monoxide Dehydrogenase Reveals a [Ni-4Fe-5S] Cluster John Lenard -- UMDNJ-Robert Wood Johnson Medical School Separate Roles for the Golgi Apparatus and Lysosomes in the Sequestration of Drugs in the Multidrug-Resistant Human Leukemic Cell Line HL-60 Weak Base Permeability Characteristics Influence the Intracellular Sequestration Site in the Multidrug-Resistant Human Leukemic Cell Line HL-60 Small Cargo Proteins and Large Aggregates Can Traverse the Golgi by a Common Mechanism without Leaving the Lumen of the Cisternae Peri-Golgi Vesicles Contain Retrograde but Not Anterograde Proteins Consistent with the Cisternal Progression Model of Intra-Golgi Transport Crucial Step in Cholesterol Homeostasis: Sterols Promote Binding of SCAP to INSIG-1, a Membrane Protein that Facilitates Retention of SREBPs in ER Compartmental Specificity of Cellular Membrane Fusion Encoded in SNARE Proteins Topological Restriction of SNARE-Dependent Membrane Fusion George R. Lenz -- NeoGenesis, Inc. Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice N-[[(5-Methyl-3-phenylisoxazol-4-yl)-phenyl]sulfonyl]propanamide, Sodium S alt, Parecoxib Sodium: A Potent and Selective Inhibitor of COX-2 for Parenteral Administration David Levens -- Laboratory of Pathology, National Cancer Institute Generation of Superhelical Torsion by ATP-Dependent Chromatin Remodeling Activities * SWI/SNF Chromatin Remodeling Requires Changes in DNA Topology Steven V. Ley -- University of Cambridge The First Lewis Acid-Catalyzed Allylboronate Additions to Aldehydes Evolving Cascades: The Claisen Rearrangement in the Development of Tandem Sequences of Three or More Reactions Rhodium-Catalyzed Coupling of Heterocycles and Alkenes: A Novel Mechanism of C-H Activation Benzotriazoles in Solid-Phase Organic Chemistry New Catalysts for Olefin Metathesis The Bestmann Ylide as a Multi-Purpose Wittig Reagent New Strategies for Organic Catalysis: The First Highly Enantioselective Organocatalytic Diels-Alder Reaction Deracemization of Baylis-Hillman Adducts Anatoliy Li -- Wellcome Trust Biocentre, University of Dundee, Dundee, UK Steps Leading to the Initiation of Replication: Where We Are and Where We May Be Going Chao-Jun Li -- Tulane University Organic Synthesis via Carbon-Carbon Bond Formations in Water Jie Jack Li -- Pfizer Global Research & Development Discovery of a New Class of Anilinoquinazoline Inhibitors with High Affinity and Specificity for the Tyrosine Kinase Domain of c-Src Molecular Properties That Influence the Oral Bioavailability of Drug Candidates Pyrazole Urea-Based Inhibitors of p38 MAP Kinase: From Lead Compound to Clinical Candidate PTP1B Inhibition and Antihyperglycemic Activity in the ob/ob Mouse Model of Novel 11 -Arylbenzo[b]naphtho[2,3-d]furans and 11 -Arylbenzo[b]naphtho[2,3-d]thiophenes Xiaobing Li -- The R.W. Johnson Pharmaceutical Research Institute Design, Synthesis, and Structure-Activity Relationships of Acetylene-Based Histamine H3 Receptor Antagonists Raquel L. Lieberman -- Northwestern University Crystallographic Trapping of a Precatalytic Enzyme Complex Provides New Insight Into Dioxygen Activation at a Mononuclear Copper Center J. Limanto -- Merck & Co., Inc. Stereoselective Synthesis of trans b-Lactams Through Iridium-Catalyzed Reductive Coupling of Imines and Acrylates Eveline S. Litscher -- Mount Sinai School of Medicine Interactions Between Mouse ZP2 Glycoprotein and Proacrosin: A Mechanism for Secondary Binding of Sperm to the Zona Pellucida During Fertilization Gerald Litwack -- Thomas Jefferson Medical College, Thomas Jefferson University Smac, a Mitochondrial Protein that Promotes Cytochrome c-Dependent Caspase Activation by Eliminating IAP Inhibition Juhong Liu -- Laboratory of Pathology, National Cancer Institute Generation of Superhelical Torsion by ATP-Dependent Chromatin Remodeling Activities * SWI/SNF Chromatin Remodeling Requires Changes in DNA Topology Yun Oliver Long -- The Ohio State University Non-enzymatic Kinetic Resolution of Racemic Alcohols with Chiral Catalysts Hanno zur Loye -- University of South Carolina Synthesis, Proton Exchange, and Topochemical Dehydration of New Ruddlesden-Popper Tantalates and Titanotantalates Zhi-Bin Luo -- Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences Novel Small Organic Molecules for a Highly Enantioselective Direct Aldol Reaction John K. Lynch -- Abbott Laboratories Recent Syntheses of (+)-Brefeldin A Charles L.B. Macdonald -- The University of Texas at Austin Stable "Transient" Carbenes David Madec -- Universite Pierre et Marie Curie Unusual Regioselectivities in Palladium-Catalyzed Allylic Substitution Highly Efficient Asymmetric Alkylation and Allylation of N-(Diphenylmethylene)glycine tert-Butyl Ester with a Chiral Phase-Transfer Catalyst Jonathan L. Male -- University of Oregon A Continuous and Clean One-Step Synthesis of Nano-particulate Ce1-xZrxO2 Solid Solutions in Near-Critical Water Effects of a Nonligating Pendant Hydrogen-Bonding Group in a Metal Complex: Stabilization of an HF Complex Victor Mamane -- Max-Planck-Institut fur Kohlenforschung, Mulheim/Ruhr, Germany Platinum-Catalyzed Skeletal Rearrangement Reactions: Generating Structural Diversity by a Uniform Mechanism Giuseppe Mantovani -- ICCOM-CNR, Florence, Italy The Nature of the Active Species in Bis(imino)pyridyl Cobalt Ethylene Polymerisation Catalysts Olefin Polymerization with [Bis(imino)pyridyl CoIICl2]: Generation of the Active Species Involves CoI Palladium(II) b-Agostic Alkyl Cations and Alkyl Ethylene Complexes: Investigation of Polymer Chain Isomerization Mechanisms In Situ Monitoring of a Heterogeneous Palladium-Based Polyketone Catalyst Copolymers of Vinyl Epoxides with Carbon Monoxide Shankar Manyem -- North Dakota State University, Fargo The Nature, Limits, and Implications of Asymmetric Autocatalysis Tin-Free Radical-Mediated C-C Bond Formations Leonardo Manzoni -- University of Milano Synthesis of Difficult Cyclic Peptides by Inclusion of a Novel Photolabile Auxiliary in a Ring Contraction Strategy Solid-Phase Synthesis of Peptide C-Terminal Thioesters by Fmoc/t-Bu Chemistry Fmoc-Based Synthesis of Peptide-a-Thioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation Dana Marlin -- University of California, Santa Cruz The Electronic Structures of an Isostructural Series of Octahedral Nitrosyliron Complexes {Fe­NO}6,7,8 Elucidated by Mossbauer Spectroscopy James A. Marshall -- University of Virginia Pd-Catalyzed Borylation of Aryl Halides Carbon-Carbon Bond Formation via Palladium-Catalyzed Reductive Coupling in Air Umpolung of Chiral 2-Ethynylaziridines Indium(I)-Mediated Stereoselective Synthesis of Nonracemic 1,3-Amino Alcohols Bearing Three Chiral Centers, Catalyzed by Palladium(0) Oxidative Transmetalation as a Route toAllylboronates and In Situ Allylboranes from Allylic Halides and Alcohols James D. Martin -- North Carolina State University Chemically Tuning Between Ferromagnetism and Antiferromagnetism by Combining Theory and Synthesis in Iron/Manganese Rhodium Borides Composition Dependence of the Nucleation Energy of Iron Antimonides from Modulated Elemental Reactants Toward Separation and Purification of Olefins Using Dithiolene Complexes: An Electrochemical Approach Seamus J. Martin -- The Smurfit Institute, Trinity College, Dublin, Ireland Caspase Activation Cascades in Apoptosis P. Martinho -- University of Lisbon Isolation and Ring-Opening of New 1-Sila-3-Metallacyclobutanes (h5-C5bFe) (CO)2CH2 SiR2 Leading to a New Class of Organometallic Polymer Effects of the Protein Environment on the Structure and Energetics of Active Sites of Metalloenzymes: ONIOM Study of Methane Monooxygenase and Ribonucleotide Reductase Martin S. Masar III -- Northwestern University Resorcarene-Based Nanoarchitectures Pradip K. Mascharak -- University of California, Santa Cruz Sensing and Fixation of NO2/N2O4 by Calix[4]Arenes New Colorimetric Detection of Glucose by Means of Electron-Accepting Indicators: Ligand Substitution of [Fe(acac)3-n(phen)n]n+ Complexes Triggered by Electron Transfer from Glucose Oxidase C-H Bond Activation by a Ferric Methoxide Complex: Modeling the Rate-Determining Step in the Mechanism of Lipoxygenase Novel Zinc Fluorescent Probes Excitable with Visible Light for Biological Applications Highly Zinc-Selective Fluorescent Sensor Molecules Suitable for Biological Applications Calix[6]arenes and Zinc: Biomimetic Receptors for Neutral Molecules A Functional Model of the O-O Bond Formation by the O2-Evolving Complex in PhotosystemII The Electronic Structures of an Isostructural Series of Octahedral Nitrosyliron Complexes {Fe­NO}6,7,8 Elucidated by Mossbauer Spectroscopy O2 Activation by Nonheme Iron Complexes: A Monomeric Fe(III)­Oxo Complex Derived from O2 Mark R. Mason -- University of Toledo Di- and Triindolylmethanes: Versatile Ligands for Main Group and Transition Elements Hisao Masukata -- Osaka University, Japan S-CDK-Dependent Phosphorylation of Sld2 Essential for Chromosomal DNA Replication in Budding Yeast Jun-ichi Matsuo -- The University of Tokyo Ethenylation of Silyl Enol Ethers with Silylethyne Andrew W. Maverick -- Louisiana State University Synthesis and Stabilization of Stibine for Low-Temperature Chemical Vapor Deposition of Carbon-Free Antimony Films Laura McAtee -- The R. W. Johnson Pharmaceutical Research Institute High-Affinity, Non-Peptide Agonists for the ORL1 (Orphanin FQ/Nociceptin) Receptor William McElroy -- University of Maryland Alternative Modular Polyketide Synthase Expression Controls Macrolactone Structure Michele A. McGuirl -- Montana State University/Bozeman Amidation of Bioactive Peptides: The Structure of Peptidylglycine a-Hydroxylating Monooxygenase Douglas K. McLemore -- Colorado State University Quantum Chemical Calculations and Experimental Evidence for O-Bonding of Carbon Monoxide to Alkali Metal Cations in Zeolites Infrared Spectra and Density Functional Calculations for OMCO, OM-(h2-CO), OMCO+, and OMOC+(m D V, Ti) in Solid Argon Matthew D. McReynolds -- University of Kansas The Three-Component Boronic Acid Mannich Reaction: Structural Diversity and Stereoselectivity Thomas J. Meade -- Northwestern University Azidoruthenium(III) Complexes as Precursors for Molecular Nitrogen and Nitrene Complexes Patrick Mehlen -- University of Lyon, Villeurbanne, France The Dependence Receptor UNC5H2/B Mediates p53-Dependent Apoptosis Ram C. Mehrotra -- University of Rajasthan, Jaipur, India Heterobimetallic Bismuth-Transition Metal Salicylate Complexes as Molecular Precursors for Ferroelectric Synthesis and Structure of Bi 2 M 2 (sal)4 (Hsal)4 (OR)2 [M = Nb, Ta; R = CH 2 CH 3 , CH(CH 3 ) 2 ], Bi 2 Ti 3 (sal)8 (Hsal)2 ,and Bi 2 Ti 4 (OiPr)(sal)10 (Hsal) (sal = O 2 CC 6 H 4 -2-O; Hsal = O 2 CC 6 H 4 -2-OH) (RO)2Ta[tris(2-oxy-3,5-dimethylbenzyl)amine]: Structure and Lactide Polymerization Activities Synthesis and Characterization of Volatile, Fluorine Free b-Ketoiminate Lanthanide MOCVD Precursors and Their Implementation in Low-Temperature Growth of Epitaxial CeO2Buffer Layers for Superconducting Electronics Oligomerization and Oxide Formation in Bismuth Aryl Alkoxides: Synthesis and Characterization of Bi4 (m4-O)(m-OC6F5)6{m3-OBi(m-OC6F5)3}2 C6H5CH3) ,Bi8(m4-O)2 (m-OC6F5)16 ,Bi6(3-O)4(3-OC6F5) f 3-OBi(OC6F5)3g 3,NaBi4(4-O)2(OC6F5)9(THF)2,andNa2Bi4(-O)2 (OC6F5)10 (THF)2 Nanocrystalline Metal Oxides as New Adsorbants for Air Purification Scandium Alkoxides: The First Mixed-Ligand Alkoxides Containing the [M5O(OR)8] Core, Scandium Alkoxoaluminates Synthesis of Arene-Soluble Mixed-Metal Zr/Ce, Zr/Y, and Related {[Zr2(OPri)9]LnX2}n Complexes Using Dizirconium Nonaisopropoxide Ligand Synthesis Structure and Properties of Mononuclear Oxovanadium(V) Alkoxides Incorporating Chelating Ethane-1,2-diol and Propane-1,2-diol Maria Mendez -- Max-Planck-Institut fur Kohlenforschung, Mulheim/Ruhr, Germany Platinum-Catalyzed Skeletal Rearrangement Reactions: Generating Structural Diversity by a Uniform Mechanism Christophe Michon -- Iowa State University, Ames Laboratory, U.S. Department of Energy Novel Chiral Functionalized N-Heterocyclic Carbenes and Their Rhodium(I) Complexes: Applications in Asymmetric Catalysis Michael M. Miller -- University of California, Los Angeles Evaluation of Isoprenoid Conformation in Solution and in the Active Site of Protein-Farnesyl Transferase Using Carbon-13 Labeling in Conjunction with Solution- and Solid-State NMR Tomoko Mineno -- University of Mississippi Potent, Low-Molecular-Weight Non Peptide Inhibitors of Matarial Aspartyl Protease Plasmepsin ll Chad A. Mirkin -- Northwestern University The Sliding Torus: Catalytic Molecular Rings as Mimics for Natural Processive Enzymes Sergei M. Mirkin -- University of Illinois at Chicago, College of Medicine Editorial Molecular Models for Repeat Expansions Lester A. Mitscher -- University of Kansas The Biology-Chemistry Interface: A Tribute to Koji Nakanishi Marta Mollerach -- Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires The Molecular Characterization of the First Autolytic Lysozyme of Streptococcus pneumoniae Reveals Evolutionary Mobile Domains Karine Monier -- The Scripps Research Institute Phospho-histone Antibody Immunofluorescence for Analysis of Cell Cycle Progression in G2 and Prophase Joel D. Moore -- University of Kansas Hypervalent Iodine-Promoted Phenolic Oxidations: Generation of a Highly Versatile o-Quinone Template Susan Moore -- University of Victoria Chromodomains Are Protein-RNA Interaction Modules Global Histone Acetylation and Deacetylation in Yeast M. Mora -- University of Lisbon New Model for a Theoretical Density Functional Theory Investigation of the Mechanism of the Carbonic Anhydrase: How Does the Internal Bicarbonate Rearrangement Occur? New Rhenium(I) Polypyridine Biotin Complexes that Show Luminescence Enhancement and Lifetime Elongation upon Binding to Avidin The First Photocrystallographic Evidence for Light-Induced Metastable Linkage Isomers of Ruthenium Sulfur Dioxide Complexes Matt Mortensen -- West Virginia University Several Approaches to Perhydrohistrionicotoxin: Setting an Azaspirocenter Ashish K. Mukherjee -- Chembiotek Research International, Calcutta, India, and Biomarin Pharmaceutical Inc., Novato, CA Novel Synthetic Inhibitors of Selection-Mediated Cell Adhesion: Synthesis of 1,6-Bis [3-(3-carboxy-methylphenyl)-4-(O-a-D-Mannopyranosyl)phenyl] hexane (TBC 1269) Jerry A. Murry -- Merck & Co., Inc. Thiazolium-Catalyzed Cross-Coupling of Aldehydes with Acylimines: A New Method for the Synthesis of a-Amidoketones Brian J. Myers -- Wayne State University Thiol Ester-Boronic Acid Coupling for the Synthesis of Ketones under Neutral Conditions Jacqueline L. Naffin -- Center for Biomedical Inventions, University of Texas Southwestern Medical Center Display Cloning: Functional Identification of Natural Product Receptors Using cDNA-Phage Display Sajiv K. Nair -- University of Kansas An Efficient Gram-Scale Synthesis of (+)-Discodermolide Itaru Nakamura -- Tohoku University, Japan Room-Temperature Alkyl-Alkyl Suzuki Cross-Coupling of Alkyl Bromides that Possess b-Hydrogens Koichi Narasaka -- The University of Tokyo A Mandala-Patterned Bandanna-Shaped Porphyrin Oligomer, C1244H1350N 84Ni20O88, Having a Unique Size Geometry Michael L. Neidig -- Stanford University Three-Dimensional Structure of a Purple Lipoxygenase Sven Nerdinger -- Morphochem AG, Munich, Germany New Heterocycle Synthesis by Using Bifunctional Reactants in MCR Chemistry: The Use of Arylglyoxales and Cinnamaldehyde in the Ugi-4CR and Passerini-3CR Julie Neuberg -- University of Rochester Medical Center Methylation of Histone H3 by COMPASS Requires Ubiquitination of Histone H2B by Rad6 SonBinh T. Nguyen -- Northwestern University A Novel Class of Ruthenium Catalysts for Olefin Metathesis Kenneth M. Nicholas -- University of Oklahoma Palladium-Catalyzed Oxidative Kinetic Resolution of Secondary Alcohols Francesco Nicotra -- University of Milano-Bicocca Sugar-Derived Amino Acids: Powerful Secondary Structure-Inducing Elements in the Design of Novel Peptidomimetics Boguslaw Nocek -- Utah State University Crystal Structure of a Carbon Monoxide Dehydrogenase Reveals a [Ni-4Fe-5S] Cluster Crystal Structure of a Novel Red Copper Protein from Nitrosomonas europaea Steven P. Nolan -- University of New Orleans Transition Metal-Carbene Complexes in Homogeneous Catalysis Laura E. Norwood -- University of Iowa Deciphering the Code of Silence: Mechanisms of Gene Repression With Connections to Human Disease Juan C. Noveron -- University of California, Santa Cruz A Functional Model of the O-O Bond Formation by the O2-Evolving Complex in PhotosystemII Ryoji Noyori -- Nagoya University Microencapsulated Catalysts: Catalytic Asymmetric Synthesis Using a Recoverable and Reusable Polymer-Supported Catalyst Melinda Nugent -- Columbia University Stereoselective Interaction of D- and L-Ribose Mediated by Divalent Lead George O'Doherty -- West Virginia University Stereocontrolled Total Synthesis of (+)-Streptazolin Several Approaches to Perhydrohistrionicotoxin: Setting an Azaspirocenter Alan B. Oelkers -- University of Oregon Time-Resolved Spectroscopic Studies of B12 Coenzymes: A Comparison of the Primary Photolysis Mechanism in Methyl-, Ethyl-, n-Propyl-, and 5¢-Deoxyadenosylcobalamin Martin Oestreich -- Westfalische Wilhelms-Universit at Munster, Germany Stereospecific Preparation of Highly Enantiomerically Enriched Organomagnesium Reagents Eugene Oh -- Department of Biochemistry and Molecular Biology, Division of Reproductive Biology, Johns Hopkins University, Bloomberg School of Public Health Getting Sperm and Egg Together: The Molecules of Mammalian Gamete Membrane Interactions Robert L. Osborne -- University of South Carolina Preparation of Artificial Metalloenzymes by Insertion of Chromium (III) Schiff Base Complexes Into Apomyoglobin Mutants Spectroscopic Characterization and Ligand-Binding Properties of Chlorite Dismutase from the Chlorate Respiring Bacterial Strain GR-1 Robert L. Paddock -- Northwestern University A Novel Class of Ruthenium Catalysts for Olefin Metathesis Tarasankar Pal -- Indian Institute of Technology Molecular Photovoltaics Sensitization of TiO2 by Supramolecules Containing Zinc Porphyrins and Ruthenium-Polypyridyl Complexes Nanoparticles with Raman Spectroscopic Fingerprints for DNA and RNA Detection Ferritin-Mediated Photocatalytic Synthesis of Copper Nanoparticles James S. Panek -- Boston University Efficient Activation of Aromatic C-H Bonds for Addition to C-C Multiple Bonds Sudipa Panigrahi -- Indian Institute of Technology Molecular Photovoltaics Sensitization of TiO2 by Supramolecules Containing Zinc Porphyrins and Ruthenium-Polypyridyl Complexes Nanoparticles with Raman Spectroscopic Fingerprints for DNA and RNA Detection Ferritin-Mediated Photocatalytic Synthesis of Copper Nanoparticles Leo A. Paquette -- The Ohio State University Recent Synthetic Applications of the Tandem Staudinger/Aza-Wittig Reaction New Synthetic Tactics Designed to Access Diynes and Polyynes The Diverse Challenges that Face the Stereocontrolled Elaboration of Natural Products Incorporating an Oxygenated Five-Membered Ring Non-enzymatic Kinetic Resolution of Racemic Alcohols with Chiral Catalysts [6p + 2p] and [6p + 4p] Higher-Order Cycloadditions and Their Deployment in Total Synthesis Domingo Gomez Pardo -- Laboratoire de Chimie Organique, Associe au CNRS, ESPCI, Paris, France Synthesis of Substituted Piperidines via Aziridinium Intermediates: Synthetic Applications Carol E. Parker -- University of North Carolina Introduction to Proteomics: Tools for the New Biology Michael H. Parker -- The R.W. Johnson Pharmaceutical Research Institute Assembly of b-Amyloid Aggregates at the Molecular Level Jon R. Parquette -- The Ohio State University A Pyridylsilyl Group Expands the Scope of the Intermolecular Pauson-Khand Reactions Developments in Fluorous Mitsunobu Chemistry Rhodium Catalyzed Ortho-Alkylation of Aromatic Aldimines and Ketimines with Olefins via C-H Bond Activation Amy Parr -- University of Utah Mono-, Di-, Tri-, and Tetracarbonyls of Copper(I), Including the Structures of Cu(CO)2(1-Bn-CB11 F11) and Cu(CO)4][1-Et-CB11 F11] Kalyani Patil -- North Dakota State University, Fargo Tin-Free Radical-Mediated C-C Bond Formations Nitin T. Patil -- Tohoku University Enantioselective Catalytic Allylation of Carbonyl Groups: Umpolung of p-Allyl Palladium Complexes Akshay Patny -- University of Mississippi Novel Tricyclic a-Alkoxyphenyl Propanoic Acid Derivatives: Dual PPARa/g Agonists with Hypolipidemic and Antidiabetic Activity Apurba K. Patra -- University of California, Santa Cruz Sensing and Fixation of NO2/N2O4 by Calix[4]Arenes C-H Bond Activation by a Ferric Methoxide Complex: Modeling the Rate-Determining Step in the Mechanism of Lipoxygenase K. Pattabiraman -- Stanford University Cooperative Chemical Sensing with Bis-Tritylacetylenes: Pinwheel Receptors with metal lon recognition Properties Noel M. Paul -- The Ohio State University Developments in Fluorous Mitsunobu Chemistry Christopher E. Pearson -- The Hospital for Sick Children, Toronto, Ontario, Canada, and The University of Toronto The Complex Nature of Trinucleotide Repeat Instability R. Lee Penn -- The Johns Hopkins University Discrete Atom Imaging of One-Dimensional Crystals Formed within Single-Walled Carbon Nanotubes Francesco Peri -- University of Milano-Bicocca Sugar-Derived Amino Acids: Powerful Secondary Structure-Inducing Elements in the Design of Novel Peptidomimetics Priya Perumalsamy -- Columbia University Stereoselective Interaction of D- and L-Ribose Mediated by Divalent Lead David H. Petering -- University of Wisconsin-Milwaukee Aqueous Coordination Chemistry of Quinoline-Based Fluorescence Probes for the Biological Chemistry of Zinc Coordination and Fluorescence of the Intracellular Zn2+ Probe [2-Methyl-8-(4-toluenesulfonamido)-6-quinolyloxy]Acetic Acid (Zinquin A) in Ternary Zn2+ Complexes Fluorescent Sensors for Zn2+ Based on a Fluorescein Platform: Synthesis, Properties and Intracellular Distribution A Tautomeric Zinc Sensor for Ratiometric Fluorescence Imaging: Application to Nitric Oxide-Induced Release of Intracellular Zinc A Reevaluation of Neuronal Zinc Measurements: Artifacts Associated With High Intracellular Dye Concentration John W. Peters -- Montana State University Crystal Structure of Naphthalene Dioxygenase: Side-on Binding of Dioxygen to Iron Crystallographic and Spectroscopic Characterization of a Nonheme Fe(IV)=O Complex Determination of the Structure of Escherichia coli Glyoxalase I Suggests a Structural Basis of Differential Metal Activation Crystal Structure of a Carbon Monoxide Dehydrogenase Reveals a [Ni-4Fe-5S] Cluster Crystal Structure of a Novel Red Copper Protein from Nitrosomonas europaea C.L. Peterson -- UMASS Medical School Targeting a SWI/SNF-Related Chromatin Remodeling Complex to the Beta-Globin Promoter in Erythroid Cells Michael C. Pirrung -- Duke University Fluorous Triphasic Reactions: Transportative Deprotection of Fluorous Silyl Ethers with Concomitant Purification Discovery of a Catalytic Asymmetric Phosphorylation Through Selection of a Minimal Kinase Mimic: A Concise Total Synthesis of D-Myo-Inositol-1-Phosphate Production by Quantitative Photolithographic Synthesis of Individually Quality Checked DNA Microarrays Rapid and Selective Selenium-Mediated Autoligation of DNA Strands Michael D. Pluth -- University of California, Berkeley Encapsulation of Cationic Organometallic Guests by a Chiral Self-Assembled Supramolecular Cage: Enantioselective Binding, Dynamic Resolution, and Selective C–H Bond Activation Kenneth R. Poeppelmeier -- Northwestern University A Novel Class of Ruthenium Catalysts for Olefin Metathesis Resorcarene-Based Nanoarchitectures Giovanni Poli -- Université Pierre et Marie Curie (Paris VI), France Palladium-Catalyzed Cyclization of Allylsilanes With Nucleophilic Displacement of the Silyl Group Transition Metal-Catalyzed Pseudo-Domino Sequences: The Development of a New Concept Unusual Regioselectivities in Palladium-Catalyzed Allylic Substitution Palladium-Catalyzed Cyclization of Allylsilanes with Nucleophilic Displacement of the Silyl Group Highly Efficient Asymmetric Alkylation and Allylation of N-(Diphenylmethylene)glycine tert-Butyl Ester with a Chiral Phase-Transfer Catalyst Aminocyclopentitols via Photohydration of N-Alkylpyridinium Salts Regio- and Stereo-Control in Rhodium-Catalyzed Allylic Substitutions Rinaldo Poli -- Laboratoire de Chimie de Coordination, Toulouse, France Hydroamination of Vinylarenes: Full Regioselectivity Control by the Choice of the Catalyst Precursors to Water-Soluble Dinitrogen Carriers. Synthesis of Water-Soluble Complexes of Iron(II) Containing Water-Soluble Chelating Phosphine Ligands of the Type 1,2-Bis[bis(hydroxyalkyl) phosphino]ethane A Carbon-Free Sandwich Complex [(P5)2-)Ti2- Transmission of trans Effects in Dinuclear Complexes The Oxo Synthesis Catalyzed by Cationic Palladium Complexes: Selectivity Control by Neutral Ligand and Anion Aqueous Organometallic Chemistry of Ruthenium(II). Aquo Carbonyl Derivatives and Related Ethene Hydrocarboxylation in Fully Aqueous Solvent Synthesis, Dynamic Behavior, and X-ray Crystal Structure of [Li(tmed)]3[WH(C2H4)4] Iron and Cobalt Ethylene Polymerization Catalysts Bearing 2,6-Bis(imino)pyridyl Ligands: Synthesis, Structures, and Polymerization Studies Mechanistic Aspects of Ethylene Polymerization by Iron(II)-Bisimine Pyridine Catalysts: A Combined Density Functional Theory and Molecular Mechanics Study Kenneth R. Poeppelmeier -- Northwestern University Characterization of the Manganese Oxide Produced by Pseudomonas putida Strain MnB1 Jeffery B. Press -- CambridgeSoft Corporation, Cambridge, Massachuestts The Rich and Diverse Spectrum of Organic Chemistry in the Millennium: Report from the 37th National Organic Symposium Guillaume Prestat -- Université Pierre et Marie Curie (Paris VI), France Palladium-Catalyzed Cyclization of Allylsilanes With Nucleophilic Displacement of the Silyl Group Transition Metal-Catalyzed Pseudo-Domino Sequences: The Development of a New Concept Palladium-Catalyzed Cyclization of Allylsilanes with Nucleophilic Displacement of the Silyl Group Aminocyclopentitols via Photohydration of N-Alkylpyridinium Salts Adam J. Preston -- The Ohio State University A Pyridylsilyl Group Expands the Scope of the Intermolecular Pauson-Khand Reactions Rhodium Catalyzed Ortho-Alkylation of Aromatic Aldimines and Ketimines with Olefins via C-H Bond Activation Glenn D. Prestwich -- The University of Utah Pursuit of Optimal Carbohydrate-Based Anticancer Vaccines: Preparation of a Multiantigenic Unimolecular Glycopeptide Containing the Tn, MBrl, and LewisY Antigens The Design, Synthesis, and Evaluation of Molecules that Enable or Enhance Cellular Uptake: Peptoid Molecular Transporters Simona Prosperini -- Università del Piemonte Orientale, Novara and Università di Parma The Synthesis of the Thapsigargins Terry M. Rabinowitz -- University of Rochester A Possible Role for the Covalent Heme-Protein Linkage in Cytochrome c Revealed via Comparison of N-Acetylmicroperoxidase-8 and a Synthetic, Monohistidine-Coordinated Heme Peptide Jeffrey J. Rack -- Ohio University Photoinduced Ligand Isomerization in Dimethyl Sulfoxide Complexes of Ruthenium(II) Carbonyl Derivatives of Chloride­Dimethyl Sulfoxide-Ruthenium(III) Complexes: Synthesis, Crystal Structure, and Reactivity of s[(DMSO)2H][trans-RuCl4(DMSO)(CO)] and [mer,cis-RuCl 3(DMSO)2(CO)] Tracy L. Rankin -- National Institute of Child Health and Human Development The Crystal Structure of a Fusagenic Sperm Protein Reveals Extreme Surface Properties Kenneth N. Raymond -- Professor of Chemistry University of California, Berkeley Encapsulation of Cationic Organometallic Guests by a Chiral Self-Assembled Supramolecular Cage: Enantioselective Binding, Dynamic Resolution, and Selective C–H Bond Activation From Coello to Inorganic Chemistry: A Lifetime of Reactions Kelly Regula -- St. Boniface General Hospital Research Centre and University of Manitoba, Winnipeg, Manitoba, Canada A Novel Role for the Mitochondrial Death Proteins Nix and BNIP3 in Cardiac Cell Death and Heart Failure Paul J. Reider -- Merck & Co., Inc. Thiazolium-Catalyzed Cross-Coupling of Aldehydes with Acylimines: A New Method for the Synthesis of a-Amidoketones Oliver Reiser -- Universität Regensburg Tandem Epoxidation/Stereoselective Intramolecular [4 + 3] Cycloaddition Reaction Cyclopropanation with Fischer Acyloxycarbene Complexes: Preparation of Cyclopropane and Cycloheptane-Fused g-Lactones A Demonstration of the Primary Stereoelectronic Effect in the Baeyer-Villiger Oxidation of a-Fluorocyclohexanones The Photochemistry of 2-(1-Naphthyl)ethyl Benzoates: Cycloaddition and Intramolecular Exciplex Formation Allen B. Reitz -- The R.W. Johnson Pharmaceutical Research Institute Assembly of b-Amyloid Aggregates at the Molecular Level Synthesis of Cyclic Peptides by Ring-Closing Metathesis Thomas G. Richmond -- University of Utah Mono-, Di-, Tri-, and Tetracarbonyls of Copper(I), Including the Structures of Cu(CO)2(1-Bn-CB11 F11) and Cu(CO)4][1-Et-CB11 F11] Hydrodefluorination of Fluorobenzene and 1,2-Difluorobenzene under Mild Conditions over Rhodium Pyridylphosphine and Bipyridyl Complexes Tethered on a Silica-Supported Palladium Catalyst James H. Rigby -- Wayne State University Thiol Ester-Boronic Acid Coupling for the Synthesis of Ketones under Neutral Conditions Enantioselective Claisen Rearrangements: Development of a First Generation Asymmetric Acyl-Claisen Reaction Christina A. Risatti -- University of Notre Dame Biomimetic Synthesis of Polycyclic Natural Products from Acyclic Precusrsors Valentin Rodionov -- University of Maryland Biosynthesis of Complex Polyketides in a Metabolically Engineered Strain of E. coli Felix Rodriguez -- University of Cambridge, United Kingdom Deracemization of Baylis-Hillman Adducts Richard J. Roller -- The University of Iowa Herpes Simplex Virus Multiprotein Machines as Therapeutic Targets: Progress and Promise S.D. Roman -- Newcastle University Progesterone Responses in Human Spermatozoa Antonio Rosato -- Center for Magnetic Resonance, University of Florence Calculation of z-Coordinates and Orientational Restraints Using a Metal Binding Tag Mary K. Rosenberg -- University of Maryland Novel Natural Products from Soil DNA Libraries in a Streptomycete Host Amy C. Rosenzweig -- Northwestern University Crystallographic Trapping of a Precatalytic Enzyme Complex Provides New Insight Into Dioxygen Activation at a Mononuclear Copper Center David P. Rotella -- Bristol-Myers Squibb A Nonpeptidyl Mimic of Superoxide Dismutase with Therapeutic Activity in Rats Small-Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen Fenchylamine Sulfonamide Inhibitors of Amyloid b Peptide Production by the g-Secretase Proteolytic Pathway: Potential Small Molecule Therapeutic Agents for the Treatment of Alzheimer's Disease Design of Potent Inhibitors for Human Brain Memapsin 2 (b-Secretase) A Cholesterol Ester Transfer Protein Inhibitor Attenuates Atherosclerosis in Rabbits Brian W. Rous -- Northwestern University The ATP Hydrolytic Activity of Purified ZntA, a Pb(II)/Cd(II)/Zn(II)-Translocating ATPase from Escherichia coli Tomislav Rovis -- Colorado State University Metal and Nonmetal Catalysts for Carbon-Carbon Bond-Forming Reactions Leading to Desymmetrized 1,4-Dicarbonyl Compounds John M. Rowland -- University of California, Santa Cruz O2 Activation by Nonheme Iron Complexes: A Monomeric Fe(III)­Oxo Complex Derived from O2 Xavier Saelens -- Ghent University, Belgium Type II Autophagic Cell Death and Death-Associated Protein Kinases Hidehiro Sakurai -- The University of Tokyo A Mandala-Patterned Bandanna-Shaped Porphyrin Oligomer, C1244H1350N 84Ni20O88, Having a Unique Size Geometry Julia E. Salas -- Stanford University Dioxygen Binds End-on to Mononuclear Copper in a Precatalytic Enzyme Complex M.L. Samuels -- UMASS Medical School Targeting a SWI/SNF-Related Chromatin Remodeling Complex to the Beta-Globin Promoter in Erythroid Cells Ian Saratovsky -- Northwestern University Characterization of the Manganese Oxide Produced by Pseudomonas putida Strain MnB1 Magnesium Manganese Oxide Nanoribbons: Synthesis, Characterization, and Catalytic Application Andrea S. Saurage -- Duke University Rapid and Selective Selenium-Mediated Autoligation of DNA Strands Andreas Schall -- Universität Regensburg Tandem Epoxidation/Stereoselective Intramolecular [4 + 3] Cycloaddition Reaction Aaron Schechter -- Fairchild Center for Biological Sciences Columbia University Prebiotic Routes for the Synthesis and Separation of Ribose New Thoughts on the Origin of Biochirality New Thoughts on the Origin of Biochirality Current Status of the RNA-Only World Ronald L. Schnaar -- The Johns Hopkins School of Medicine Identification and Characterization of a Novel Siglec, Siglec-7, Expressed by Human Natural Killer Cells and Monocytes Siglec-8: A Novel Eosinophil-Specific Member of the Immunoglobulin Superfamily Michael R. Schrimpf -- Abbott Laboratories Recent Syntheses of (+)-Brefeldin A Maria Schultzberg -- European Molecular Biology Laboratory (EMBL), Heidelberg Stochastic Sensing of Organic Analytes by a Pore-Forming Protein Containing a Molecular Adapter Stefan Schuster -- Max Delbruck Center for Molecular Medicine, Berlin The Large-Scale Organization of Metabolic Networks Carlo Scolastico -- University of Milano Synthesis of Difficult Cyclic Peptides by Inclusion of a Novel Photolabile Auxiliary in a Ring Contraction Strategy W. Michael Seganish -- University of Maryland Design and Synthesis of Pyrrolidine-5,5-trans-lactams as Novel Mechanism Based Inhibitors of Human Cytomegalovirus Protease Konrad Seppelt -- Freie Universitat Berlin The Isolation of Uncomplexed P42- The Structures of Polyboron Fluorides Synthesis and Structure of Na3N N5+, cis- and trans-N2O22- Nathan Sharon -- Weizmann Institute of Science Proteoglycan Protocols: Methods in Molecular Biology, Volume 171 Scott M. Sheehan -- Eli Lilly and Company Proline-Catalyzed Asymmetric Mannich Reactions: The Highly Enantioselective Synthesis of Amino Acid Derivatives and 1,2-Amino Alcohols Mukund P. Sibi -- North Dakota State University The Nature, Limits, and Implications of Asymmetric Autocatalysis Tin-Free Radical-Mediated C-C Bond Formations Radu Silaghi-Dumitrescu -- University of Georgia Tuning the Electronic Structure of Octahedral Iron Complexes {FeL-X-}(L = 1-Alkyl-4,7-bis(4-tert-butyl-2-mercaptobenzyl)-1,4,7-triazacyclononane, X = Cl, CH3O, CN, NO): The S = 1/2 Ü S = 3/2 Spin Equilibrium of {FeLPr(NO)} High-Resolution Crystal Structures and Spectroscopy of Native and Compound I Cytochrome c Peroxidase Tomas Simonsson -- Chalmers University of Technology, Sweden TIN2, a New Regulator of Telomere Length in Human Cells Identification of Human Rap:Implications for Telomere Evolution B. Singer -- University of California, Berkeley Human Thymine DNA Glycosylase (TDG) and Methyl-CpG-Binding Protein 4 (MBD4) Excise Thymine Glycol (Tg) from a Tg:G Mispair The Main Role of Human Thymine-DNA Glycosylase Is Removal of Thymine Produced by Deamination of 5-Methylcytosine and Not Removal of Ethenocytosine Investigation of the Substrate Spectrum of the Human Mismatch-Specific DNA N-Glycosylase MED1 (MBD4): Fundamental Role of the Catalytic Domain Biphasic Kinetics of the Human DNA Repair Protein MED1 (MBD4), a Mismatch-Specific DNA N-Glycosylase Molecular Basis for Discriminating Between Normal and Damaged Bases by the Human Alkyladenine Glycosylase, AAG Anirudh Singh -- University of Rajasthan, Jaipur, India Heterobimetallic Bismuth-Transition Metal Salicylate Complexes as Molecular Precursors for Ferroelectric Synthesis and Structure of Bi 2 M 2 (sal)4 (Hsal)4 (OR)2 [M = Nb, Ta; R = CH 2 CH 3 , CH(CH 3 ) 2 ], Bi 2 Ti 3 (sal)8 (Hsal)2 ,and Bi 2 Ti 4 (OiPr)(sal)10 (Hsal) (sal = O 2 CC 6 H 4 -2-O; Hsal = O 2 CC 6 H 4 -2-OH) (RO)2Ta[tris(2-oxy-3,5-dimethylbenzyl)amine]: Structure and Lactide Polymerization Activities Synthesis and Characterization of Volatile, Fluorine Free b-Ketoiminate Lanthanide MOCVD Precursors and Their Implementation in Low-Temperature Growth of Epitaxial CeO2Buffer Layers for Superconducting Electronics Oligomerization and Oxide Formation in Bismuth Aryl Alkoxides: Synthesis and Characterization of Bi4 (m4-O)(m-OC6F5)6{m3-OBi(m-OC6F5)3}2 C6H5CH3) ,Bi8(m4-O)2 (m-OC6F5)16 ,Bi6(3-O)4(3-OC6F5) f 3-OBi(OC6F5)3g 3,NaBi4(4-O)2(OC6F5)9(THF)2,andNa2Bi4(-O)2 (OC6F5)10 (THF)2 Nanocrystalline Metal Oxides as New Adsorbants for Air Purification Scandium Alkoxides: The First Mixed-Ligand Alkoxides Containing the [M5O(OR)8] Core, Scandium Alkoxoaluminates Synthesis of Arene-Soluble Mixed-Metal Zr/Ce, Zr/Y, and Related {[Zr2(OPri)9]LnX2}n Complexes Using Dizirconium Nonaisopropoxide Ligand Synthesis Structure and Properties of Mononuclear Oxovanadium(V) Alkoxides Incorporating Chelating Ethane-1,2-diol and Propane-1,2-diol Heather M. Sklenicka -- University of Minnesota-Twin Cities Recent Approaches to cis-Azadecalins: Synthesis of Dendrobatid Alkaloid Pumiliotoxin C Catharine L. Smith -- Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health Snf1 - A Histone Kinase That Works in Concert with the Histone Acetyltransferase Gcn5 to Regulate Transcription Regulate Transcription K.M. Smith -- Universite de Bourgogne, Dijon, France Iron and Cobalt Ethylene Polymerization Catalysts Bearing 2,6-Bis(imino)pyridyl Ligands: Synthesis, Structures, and Polymerization Studies Mechanistic Aspects of Ethylene Polymerization by Iron(II)-Bisimine Pyridine Catalysts: A Combined Density Functional Theory and Molecular Mechanics Study Arash Soheili -- Merck & Co., Inc. Thiazolium-Catalyzed Cross-Coupling of Aldehydes with Acylimines: A New Method for the Synthesis of a-Amidoketones Marco Sola -- University of Modena and Reggio Emilia, Modena, Italy Metal-Ligand Interplay in Blue Copper Proteins Studied by 1H NMR Spectroscopy: Cu(II)-Pseudoazurin and Cu(II)-Rusticyanin A Comparison of the Inner-Sphere Reorganization Energies of Cytochromes, Iron-Sulfur Clusters and Blue Copper Proteins Edward I. Solomon -- Stanford University Dioxygen Binds End-on to Mononuclear Copper in a Precatalytic Enzyme Complex Three-Dimensional Structure of a Purple Lipoxygenase Crystal Structure of a Plant Catechol Oxidase Containing a Dicopper Center E.V. Sokurenko -- University of Washington X-ray Structure of the FimC-FimH Chaperone-Adhesin Complex from Uropathogenic Escherichia coli Alavattam Sreedhara -- Ohio State University Cluster-Mediated Conversion of Diphenylacetylene into a-Phenylcinnamaldehyde. Conversion of a Catalytic Hydroformylation Cycle Based on Isolated Intermediates Andrzej Stasiak -- Universite de Lausanne, Switzerland Positive Torsional Strain Causes the Formation of a Four-Way Junction at Replication Forks Tailed Duplex DNA Is the Preferred Substrate for Rad51 Protein-Mediated Homologous Pairing Arnold Stein -- Purdue University Developmentally Dynamic Histone Acetylation Pattern of a Tissue-Specific Chromatin Domain Polarity of Transcriptional Enhancement Revealed by an Insulator Element Dietrich Steinhuebel -- Merck & Co., Inc. (p-Allyl)palladium Complexes Bearing Diphosphinidenecyclobutene Ligands (DPCD): Highly Active Catalysts for Direct Conversion of Allylic Alcohols Alan M. Stolzenberg -- West Virginia University Hydrogenolysis of Aliphatic Carbon­Fluorine Bonds in Fluoroalkyl­Iridium Complexes to Give Hydrofluorocarbons Bernard S. Strauss -- University of Chicago Apoptotic Signaling in Response to a Single Type of DNA Lesion, O6-Methylguanine Apoptosis Triggered by DNA Damage O6-Methylguanine in Human Lymphocytes Requires DNA Replication and Is Mediated by p53 and Fas/CD95/Apo-1 Inhibiting Cell Division in Escherichia coli Has Little If Any Effect on Gene Expression Adaptation to Famine: A Family of Stationary-Phase Genes Revealed by Microarray Analysis DNA Array Analysis of Gene Expression in Response to UV Irradiation in Escherichia coli Comparative Gene Expression Profiles Following UV Exposure in Wild-Type and SOS-Deficient Escherichia coli Global Gene Expression Profiling in Escherichia coli k12: The Effects of Oxygen Availability and FNR|| Activation-Induced Cytidine Deaminase Deaminates Deoxycytidine on Single-Stranded DNA But Requires the Action of RNase Transcription-Targeted DNA Deamination by the AID Antibody Diversification Enzyme Transcription Enhances AID-Mediated Cytidine Deamination by Exposing Single-Stranded DNA on the Nontemplate Strand The Translesion DNA Polymerase Zeta Plays a Major Role in Ig and bcl-6 Somatic Hypermutation ATM Phosphorylates Histone H2AX in Response to DNA Double Strand Breaks Histone H2AX Is Phosphorylated in an ATR-Dependent Manner in Response to Replicational Stress E. coli Transcription Repair Coupling Factor (Mfd Protein) Rescues Arrested Complexes by Promoting Forward Translocation All Three SOS-Inducible DNA Polymerases (Pol II, Pol IV and Pol V) are Involved in Induced Mutagenesis Efficient Bypass of a Thymine­Thymine Dimer by Yeast DNA Polymerase, Pol n The XPV (Xeroderma Pigmentosum Variant) Gene Encodes Human DNA Polymerase n hRAD30 Mutations in the Variant Form of Xeroderma Pigmentosum Rnq1: An Epigenetic Modifier of Protein Function in Yeast Creating a Protein-Based Element of Inheritance Molecular Basis of a Yeast Prion Species Barrier Pol ?: A DNA Polymerase Required for Sister Chromatid Cohesion Steven H. Strauss -- Colorado State University Isolation and Structure of the OCNCO+ Ion Existence of the Halocarbonyl and Trifluoromethyl Cations in the Condensed Phase Quantum Chemical Calculations and Experimental Evidence for O-Bonding of Carbon Monoxide to Alkali Metal Cations in Zeolites Infrared Spectra and Density Functional Calculations for OMCO, OM-(h2-CO), OMCO+, and OMOC+(m D V, Ti) in Solid Argon Gerald Stubbs -- Vanderbilt University Structure of the Herpesvirus Major Capsid Protein Electron Cryomicroscopy and Bioinformatics Suggest Protein Fold Models for Rice Dwarf Virus Topologically Linked Protein Rings in the Bacteriophage HK97 Capsid Structure of the Reovirus Core at 3.6 A Resolution Masaharu Sugiura -- Graduate School of Pharmaceutical Sciences, The University of Tokyo, and CREST, Japan Science and Technology Corporation (JST) Palladium-Catalyzed Direct Transformation of Carboxylic Acids to Aldehydes and Ketones Kevin F. Sullivan -- The Scripps Research Institute Phospho-histone Antibody Immunofluorescence for Analysis of Cell Cycle Progression in G2 and Prophase Roger M. Sullivan -- North Carolina State University, Raleigh Composition Dependence of the Nucleation Energy of Iron Antimonides from Modulated Elemental Reactants Keith A. Sutton -- Department of Cell Biology, University of Massachusetts Medical School The Acrosome Reaction: An Example of Egg-Activated Signal Transduction in Sperm Progesterone Responses in Human Spermatozoa Willie J. Swanson -- Department of Genome Sciences, University of Washington Functional Inferences from Rapidly Evolving Reproductive Proteins Celine H. Taboy -- Duke University Ascaris Haemoglobin Is a Nitric Oxide-Activated ''Deoxygenase'' A. Tsahai Tafari -- National Institute of Environmental Health Sciences, National Institutes of Health Transcriptional Specificity of Human SWI/SNF BRG1 and BRM Chromatin Remodeling Complexes Yong Tang -- Shanghai Institute of Organic Chemistry, Shanghai, China Asymmetric Phase-Transfer Catalysis by a Rigid Quaternary Ammonium Salt Michael H. Tatham -- University of St. Andrews, St. Andrews, Scotland Ubiquitin and Ubiquitin-like Modifiers: Conserved Mechanisms and Diverse Functions Laurie Taylor -- University of South Carolina, Columbia Formation and Catalytic Roles of Compound I in the Hydrogen Peroxide-Dependent Oxidations by His 64 Mb Mutants Richard E. Taylor -- University of Notre Dame Biomimetic Synthesis of Polycyclic Natural Products from Acyclic Precusrsors Lewis Acid Induced Epoxide Rearrangement for Complex Molecule Synthesis S. Thebault -- Gladstone Institute of Virology and Immunology, San Francisco Regulation of Skeletal Myogenesis by Association of the MEF2 Transcription Factor with Class II Histone Deacetylases Alison Thompson -- Dalhousie University A Simple Resolution Procedure Using the Staudinger Reaction for the Preparation of P-Stereogenic Phosphine Oxides Asymmetric Pauson-Khand Reactions Using Camphor-Derived Chelating Thiols as Chiral Controllers Highly Efficient Catalytic Synthesis of a-Amino Acids under Phase-Transfer Conditions with a Novel Catalyst/Substrate Pair Chirality Control of a Cu(I)3(phenanthroline)2 Complex by a Sugar-Boronic Acid Interaction. A Preliminary Step Toward Total Chain Helicity Control by a Chain-End Sugar Binding Brian D. Thompson -- GlaxoSmithKline Research & Development, Research Triangle Park, NC Discovery and Mechanistic Exploration of a Novel Rhodium-Catalyzed Cyclization Christopher F. Thompson -- Merck & Co., Inc. Catalytic Enantioselective Synthesis of b2-Amino Acids Richard Tillyer -- Merck & Co., Inc. Thiazolium-Catalyzed Cross-Coupling of Aldehydes with Acylimines: A New Method for the Synthesis of a-Amidoketones A.M. Tolkovsky -- University of Cambridge, Cambridge, UK A Novel Protein Complex Linking the d2 Glutamate Receptor and Autophagy: Implications for Neurodegeneration in Lurcher Mice Peter L. Toogood -- Pfizer Global Research and Development, Ann Arbor Laboratories Structure Based Design of an Osteoclast-Selective Nonpeptide Src Homology 2 Inhibitor with In Vivo Antiresorptive Activity Dirk Trauner -- University of California, Berkeley Direct Catalytic Asymmetric Amination of Aldehydes: Synthesis of Evans Oxazolidinones and a-Amino Acids Thomas Traut -- University of North Carolina at Chapel Hill A Vertebrate Globin Expressed in the Brain Cloning, Gene Expression, and Protein Purification David J. Triggle -- State University of New York In Vitro and In Vivo Evaluation of Dihydropyrimidinone C-5 Amides as Potent and Selective b A Receptor Antagonists for the Treatment of Benign Prostatic Hyperplasia Discovery of Novel Non-Peptide CCR1 Receptor Antagonists Synthesis, Molecular Modeling, and Pharmacological Testing of Bis-Quinolinium Cyclophanes: Potent, Non-Peptidic Blockers of the Apamin-Sensitive Ca2+<-Activated K+ Channel J. Tsuji -- Tokyo Institute of Technology (Emeritus) Intramolecular Nucleophilic Addition of Aryl Bromides to Ketones Catalyzed by Palladium and Related Reactions Ruthenium(II) and Palladium(II) Complexes Mediated Addition of Ketene Silyl Ketal to Aldehydes and Ketones: Remarkable Influence of the Nature of the Ligands Room-Temperature Amination of Chloroarenes Using Saturated Carbene Ligands Irina Tsyba -- University of Southern California Neutron Diffraction Studies on Proteins Paola Turano -- University of Florence Effects of Folding on Metalloprotein Active Sites James M. Turner -- The Scripps Research Institute, La Jolla, California Regulation of Gene Expression with Synthetic DNA-Binding Ligands David R. Tyler -- University of Oregon Time-Resolved Spectroscopic Studies of B12 Coenzymes: A Comparison of the Primary Photolysis Mechanism in Methyl-, Ethyl-, n-Propyl-, and 5¢-Deoxyadenosylcobalamin A Continuous and Clean One-Step Synthesis of Nano-particulate Ce1-xZrxO2 Solid Solutions in Near-Critical Water Effects of a Nonligating Pendant Hydrogen-Bonding Group in a Metal Complex: Stabilization of an HF Complex Eric W. Uffman -- Washington University A Novel Peptide-Based Encoding System for "One-Bead One-Compound" Peptidomimetic and Small Molecule Combinatorial Libraries Victor D. Vacquier -- University of California San Diego Positive Darwinian Selection Drives the Evolution of Several Female Reproductive Proteins in Mammals Michela Valacchi -- ICCOM-CNR, Florence, Italy Enantioselective Addition of Alcohols to Ketenes Catalyzed by a Planar-Chiral Azaferrocene: Catalytic Asymmetric Synthesis of Arylpropionic Acids Enantioselective Staudinger Synthesis of b-Lactams Catalyzed by a Planar-Chiral Nucleophile Palladium-Catalyzed Arylation of Malonates and Cyanoesters Using Sterically Hindered Trialkyl-and Ferrocenyldialkylphosphine Ligands A General and Mild Copper-Catalyzed Arylation of Diethyl Malonate Asymmetric Catalysis with the Normally Unresolvable, Conformationally Dynamic 2,2¢-Bis(diphenylphosphino)-1,1¢-biphenyl (Biphep) Resolution of Pd Catalyst with tropos Biphenylphosphine (BIPHEP) Ligand by DM-DABN: Asymmetric Catalysis by an Enantiopure BIPHEP-Pd Complex Asymmetric Activation of the Pd Catalyst Bearing the tropos Biphenylphosphine (BIPHEP) Ligand with the Chiral Diaminobinaphthyl (DABN) Activator Peter Vandenabeele -- Ghent University, Belgium Type II Autophagic Cell Death and Death-Associated Protein Kinases C.L. VanDeusen -- Stanford University Cooperative Chemical Sensing with Bis-Tritylacetylenes: Pinwheel Receptors with metal lon recognition Properties P.D. Vaz -- University of Lisbon Group Transfer From Nickel Imido, Phosphinidene, and Carbene Complexes to Ethylene With Formation of Aziridine, Phosphirane, and Cyclopropane Products and Observation of the Enhancement in Enantioselectivity With Conversion for the Aziridination of Styrene Using Copper Bis(oxazoline) Complexes E. Verdin -- Gladstone Institute of Virology and Immunology, San Francisco Regulation of Skeletal Myogenesis by Association of the MEF2 Transcription Factor with Class II Histone Deacetylases Benjamin J. Vesper -- Northwestern University Resorcarene-Based Nanoarchitectures Mike Visnick -- Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company PTP1B Inhibition and Antihyperglycemic Activity in the ob/ob Mouse Model of Novel 11 -Arylbenzo[b]naphtho[2,3-d]furans and 11 -Arylbenzo[b]naphtho[2,3-d]thiophenes Novel Antiarthritic Agents with 1,2-Isothiazolidine-1,1-dioxide (g-Sultam) Skeleton: Cytokine Suppressive Dual Inhibitors of Cyclooxygenase-2 and 5-Lipoxygenase Antonin Vlcek Jr. -- Queen Mary, University of London and the J. Heyrovsky Institute of Physical Chemistry, Prague Photochemical Cycling of Iron in the Surface Ocean Mediated by Microbial Iron(III)-Binding Ligands Kinetics, Mechanism, and Spectroscopy of the Reversible Binding of Nitric Oxide to Aquated Iron(II). An Undergraduate Text Book Reaction Revisited Triplet Organometallic Reactivity under Ambient Conditions: An Ultrafast UV Pump/IR Probe Study Heteroleptic 5,5'-Disubstituted-2,2'-bipyridine Complexes of Ruthenium(II): Spectral, Electrochemical, and Structural Investigations Synthesis and Photophysical Properties of Luminescent Rhenium(I) and Manganese(I) Polypyridine Complexes Containing Pendant 1,3,4-Oxadiazole/Triarylamine Assemblies Ultrafast Electron Diffraction of Transient [Fe(CO)4]: Determination of Molecular Structureand Reaction Pathway Femtosecond Infrared Study of the Dynamics of Solvation and Solvent Caging Hydrogen Produced from Hydrohalic Acid Solutions by a Two-Electron Mixed-Valence Photocatalyst Electron Tunneling in Single Crystals of Pseudomonas aeruginosa Azurins Molecular Batteries: Ferrocenylsilylation of Dendrons, Dendritic Cores, and Dendrimers. New Convergent and Divergent Routes to Ferrocenyl Dendrimers with Stable Redox Activity Synthesis and Electrochemistry of Ferrocenyl-diazabutadiene Metal Carbonyl Complexes (Fc-DAB)M(CO)4 [M D Cr, Mo, W] The Redox Behaviour of the Family (C 60) [Mo (CO) 2 (phen) (dbm)] N (n=1-3-: A Comparison with the Analog (h2-C70)[Mo(CO)2(phen)(dbm)] (phen D 1,10-Phenanthroline; dbm D Dibutyl Maleate) Spin Crossover in Supramolecular Fe4II [2 x 2] Grid Triggered by Temperature, Pressure, and Light Transition Metal Complexes with Sulfur Ligands. Part CXLIV: Square Planar Nickel Complexes with NiS4 Cores in Three Different Oxidation States: Synthesis, X-Ray Structural and Spectroscopic Studies Femtosecond Multicolor Pump-Probe Spectroscopy of Ferrous Cytochrome c Electron Tunnelling through Water: Oxidative 2+ Quenching of Electronically Excited Ru(tpy)22+ (tpy =2,2':6,2''-terpyridine) by Ferric Ions in Aqueous Glasses at 77 K Quantitative Wavelength-Dependent Photochemistry of the [CpFe(h6-ipb)]PF6 (ipb = Isopropylbenzene) Photoinitiator Multilevel Molecular Electronic Species: Electrochemical Reduction of a [2 ð 2] CoII 4 Grid-Type Complex by 11 Electrons in 10 Reversible Steps Electronic Structure of Bis(o-iminobenzo-semiquinonato)metal Complexes (Cu, Ni, Pd): The Art of Establishing Physical Oxidation States in Transition-Metal Complexes Containing Radical Ligands Redox-Induced Indenyl Slippage in [IndCpMoL2]2+/+/0 Complexes Excitation Energies for Transition Metal Compounds from Time-Dependent Density Functional Theory: Applications to MnO4-, Ni(CO)4, and Mn2(CO)10 Optical Switching and Fluorescence Modulation Properties of Photochromic Metal Complexes Derived from Dithienylethene Ligands A Transition Metal Containing Rotaxane in Motion: Electrochemically Induced Pirouetting of the Ring on the Threaded Dumbbell Electrochemical and Spectroscopic Studies on the Reduction of the cis-(Et2- dcbpy)2 RuX2 Series of Photovoltaic Sensitizer Precursor Complexes(Et2-dcbpy = Diethyl 2,2'-bipyridine-4,4-dicarboxylate; X = Cl-, I-, NCS-, CN3) - Electrochemical and Spectroscopic Studies on the Oxidation of the cis-(Et2-dcbpy)2 RuX2 Series of Photovoltaic Sensitizer Precurs or Complexes(Et2-dcbpy D 2,20-Bipyridine-4,4-diethoxydicarboxylic Acid; X = Cl-, I-, NCS-, CN-) Electrochemistry of Multicomponent Systems: Redox Series Comprising up to 26 Reversible Reduction Processes in Polynuclear Ruthenium(II) Bipyridine-Type Complexes A Ruthenium(II) tris(2,20 -bipyridine) Derivative Possessing a Triplet Lifetime of 42 ms Gold Solubility in Supercritical Hydrothermal Brines Measured in Synthetic Fluid Inclusions Charge Separation in a Triosmium Cluster Zwitterion Revealed by Time-Resolved Microwave Conductivity: First Application of TRMC in Organometallic Chemistry Internal Conversion and Vibronic Relaxation from Higher Excited Electronic State of Porphyrins: Femtosecond Fluorescence Dynamics Studies Electron Injection and Recombination in Dye Sensitized Nanocrystalline Titanium Dioxide Films: A Comparison of Ruthenium Bipyridyl and Porphyrin Sensitizer Dyes Diagnostic Organometallic and Metallodendritic Materials for SO2 Gas Detection: Reversible Binding of Sulfur Dioxide to Arylplatinum(II) Complexes STM Imaging of a Heptanuclear Ruthenium(II) Dendrimer, Mono-Add Layer on Graphite Eric Verdin -- Gladstone Institute of Virology and Immunology, University of California, San Francisco Towards a Molecular Understanding of the Silencing of Transcription by Heterochromatin: Methylation of Histone H3 Lysine 9 Creates a Binding Site for HP1 Proteins Selective Recognition of Methylated Lysine 9 on Histone H3 by the HP1 Chromo Domain Role of Histone H3 Lysine 9 Methylation in Epigenetic Control of Heterochromatin Assembly Heather Voegtle -- University of South Carolina Effect of Distal Cavity Mutations on the Formation of Compound I in Catalase-Peroxidases Lori L. Wallrath -- University of Iowa Deciphering the Code of Silence: Mechanisms of Gene Repression With Connections to Human Disease Michael A. Walters -- Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company Synthesis and Preliminary Evaluation of a Library of Polycyclic Small Molecules for Use in Chemical Genetic Assays Dong Wang -- Tulane University Organic Synthesis via Carbon-Carbon Bond Formations in Water Yi Wang -- Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences Enantioselective Friedel-Crafts Reaction: From Stoichiometric to Catalytic Zhong Wang -- Stanford University Synthetic Heme Chemistry: The Cradle of Functional Molecules and Catalysts Paul M. Wassarman -- Brookdale Department of Molecular, Cell and Developmental Biology, Mount Sinai School of Medicine The Mammalian Egg Zona Pellucida: Structure and Function During Fertilization Christine J. Watson -- University of Cambridge, Cambridge, UK The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini ß4 Integrin-Dependent Formation of Polarized Three-Dimensional Architecture Confers Resistance to Apoptosis in Normal and Malignant Mammary Epithelium James A. Watson Jr. -- University of Maryland Total Synthesis of Nominal Diazonamides. Part 1: Convergent Preparation of the Structure Proposed for (-)-Diazonamide A. Part 2: On the True Structure and Origin of Natural Isolates Katherine D. Weaver -- Duke University High-Resolution Structure of an Alternate Form of the Ferric Ion Binding Protein from Haemophilus influenzae Emily E. Weinert -- University of Maryland A Novel Biosynthetic Pathway Providing Precursors for Fatty Acid Biosynthesis and Secondary Metabolite Formation in Myxobacteria P.A. Wender -- Stanford University A Facile C-C Bond Cleavage in Epoxides and Its Use for the Synthesis of Oxygenated Heterocycles by a Ring Expansion Strategy Cooperative Chemical Sensing with Bis-Tritylacetylenes: Pinwheel Receptors with metal lon recognition Properties Arthur Winter -- University of Maryland Halipeptins A and B: Two Novel Potent Anti-inflammatory Cyclic Depsipeptides from the Vanuatu Marine Sponge Haliclona Species L. Keith Woo -- Iowa State University Rapid, Reversible Oxygen Atom Transfer Between an Oxomanganese(V) Porphyrin and Bromide: A Haloperoxidase Mimic with Enzymatic Rates The Cyanoimido Ligand as an Oxo Analogue: Novel Approaches to the Preparations of Cyano(imino)-aza-phosphorus(V) and N-Cyanoaziridine Isolation and X-Ray Crystal Structure of an Unusual Biscarbene Metal Complex and Its Reactivity Toward Cyclopropanation and Allylic C-H Insertion of Unfunctionalized Alkenes Alkyl Exchange Reactions of Organocobalt Porphyrins: A Bimolecular Homolytic Substitution Reaction Kinetics and Mechanisms of Thermally Induced Alkane Eliminations from Silica-Supported Bis(alkyl)chromium(IV) and -vanadium(IV) Complexes Shape-Selective Ligation to Dendrimer­Metalloporphyrins Anna Woodward -- Wellcome Trust Biocentre, University of Dundee, Dundee, UK Steps Leading to the Initiation of Replication: Where We Are and Where We May Be Going John R. Woolfrey -- University of Mississippi Pursuing a Progesterone Receptor Pharmacophore: Development of Nonsteroidal Ligands for the Progesterone Receptor Genevieve B. Wortzman -- Department of Biochemistry and Molecular Biology, Division of Reproductive Biology, Johns Hopkins University, Bloomberg School of Public Health Getting Sperm and Egg Together: The Molecules of Mammalian Gamete Membrane Interactions Hong Wu -- University of Missouri-Columbia Polar Order in Crystalline Molecular Organic Materials by Rational Design Andrew H. Wyllie -- University of Cambridge, Cambridge, UK The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini ß4 Integrin-Dependent Formation of Polarized Three-Dimensional Architecture Confers Resistance to Apoptosis in Normal and Malignant Mammary Epithelium Issaku Yamada -- Nagoya University Microencapsulated Catalysts: Catalytic Asymmetric Synthesis Using a Recoverable and Reusable Polymer-Supported Catalyst Tohru Yamada -- Keio University Chiral Brønsted Acid-Catalyzed Mannich-Type Reaction Catalytic Asymmetric Acylation of Racemic Secondary Alcohols with Benzoyl Chloride in the Presence of a Chiral Diamine Yoshinori Yamamoto -- Tohoku University, Japan Enantioselective Catalytic Allylation of Carbonyl Groups: Umpolung of p-Allyl Palladium Complexes Room-Temperature Alkyl-Alkyl Suzuki Cross-Coupling of Alkyl Bromides that Possess b-Hydrogens The First Novel Direct Oxygen Atom Transfer from Hypervalent Oxido-l3-iodanes to a,b-Unsaturated Carbonyl Compounds to Give a,b-Epoxy Carbonyl Compounds The Direct Catalytic Asymmetric Aldol Reaction Using Rare Earth-Based Heterobi- and Heteropolymetallic BINOL Complexes Lili Yamasaki -- Columbia University The Retinoblastoma Tumor Suppressor (RB) Pathway Ben S. Yong -- University of New Orleans Transition Metal-Carbene Complexes in Homogeneous Catalysis A. Zamojski -- Institute of Organic Chemistry, Warsaw Chiral (E; E)-1,4-Dialkoxy-1,3-butadienes. Synthesis, Conformational Studies and Diels-Alder Reactions with Symmetric Dienophiles Franca Zanardi -- Universita del Piemonte Orientale, Novara and Universit a di Parma The Synthesis of the Anti-Malarial Natural Product Polysphorin and Analogues Using Polymer-Supported Reagents and Scavengers The Synthesis of the Thapsigargins Resurrecting the Cornforth Model for Carbonyl Addition: Studies on the Origin of the 1,2-Asymmetric Induction in Enolate Addition to Heteroatom-Substituted Aldehydes Isopavines as a New Class of Morphinomimetics The First Stereoselective Total Synthesis of Quinine The Vinylogous Intramolecular Morita-Baylis-Hillman Reaction Molecular Recognition of Carbonyl Compounds Using Aluminum Tris(2,6-diphenylphenoxide) (ATPH): New Regio- and Stereoselective Alkylation of a,b-Unsaturated Carbonyl Compounds A New Method for the One-Step Synthesis of a,a-Unsaturated Carbonyl Systems from Saturated Alcohols and Carbonyl Compounds The Synthesis of Bisorbicillinoids. An Amazing Self-Assembly of Simple Compounds into Highly Complex Natural Products The Total Synthesis of Frondosin B Yanshi Zhang -- University of Minnesota-Twin Cities Transition Metal-Catalyzed [2 + 2 + 2] Cycloadditions With Ynamides Zhiping Zheng -- University of Arizona Assembling Lanthanide Hydroxide Clusters B.S. Zhorov -- McMaster University, Hamilton, Ontario Rational Discovery of Novel Antagonists of Retinoic Acid Receptor Maoquan Zhou -- West Virginia University Stereocontrolled Total Synthesis of (+)-Streptazolin Min Zhu -- University of Rochester Medical Center Activator-Dependent Transcription from Chromatin In Vitro Involving Targeted Histone Acetylation by p300 Xiaoling Zhu -- Department of Biochemistry and Molecular Biology, Division of Reproductive Biology, Johns Hopkins University, Bloomberg School of Public Health Getting Sperm and Egg Together: The Molecules of Mammalian Gamete Membrane Interactions Samantha G. Zeitlin -- The Scripps Research Institute Phospho-histone Antibody Immunofluorescence for Analysis of Cell Cycle Progression in G2 and Prophase Jake Zimmerman -- North Dakota State University, Fargo Tin-Free Radical-Mediated C-C Bond Formations Robert W. Zoellner -- Humboldt State University High-Resolution Infrared, Millimeter-Wave, and Ab Initio Studies Dissociation Barriers for Odd-Numbered Acyclic Nitrogen Molecules N9 and N11 Theoretical Study of Potential Energy Surfaces for N12 Clusters On the Stability of N5+N5- Geoffrey Zubay -- Columbia University Stereoselective Interaction of D- and L-Ribose Mediated by Divalent Lead A Ribozyme Composed of Only Two Different Nucleotides The Glyoxylate Cycle, a Possible Evolutionary Precursor of the TCA Cycle Prebiotic Routes for the Synthesis and Separation of Ribose New Thoughts on the Origin of Biochirality New Thoughts on the Origin of Biochirality Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lympoblastic Leukemia with the Philadelphia Chromosome Biochemical Pathways May Provide Leads to Prebiotic Pathways Current Status of the RNA-Only World Synthesis of the First Nucleotides